| Literature DB >> 14668409 |
Emmanuelle Baudry1, Frantz Depaulis.
Abstract
Several neutrality tests use outgroups to infer the ancestral and derived states for polymorphism data. However, homoplasy can result in the incorrect inference of the derived variant. We show that empirically derived rates of misorientation strongly influence Fay and Wu's H-test, especially when the sample size is large.Mesh:
Year: 2003 PMID: 14668409 PMCID: PMC1462824
Source DB: PubMed Journal: Genetics ISSN: 0016-6731 Impact factor: 4.562