Literature DB >> 14660414

Antifungal 3-hydroxy fatty acids from Lactobacillus plantarum MiLAB 14.

Jörgen Sjögren1, Jesper Magnusson, Anders Broberg, Johan Schnürer, Lennart Kenne.   

Abstract

We report the identification and chemical characterization of four antifungal substances, 3-(R)-hydroxydecanoic acid, 3-hydroxy-5-cis-dodecenoic acid, 3-(R)-hydroxydodecanoic acid and 3-(R)-hydroxytetradecanoic acid, from Lactobacillus plantarum MiLAB 14. The concentrations of the 3-hydroxy fatty acids in the supernatant followed the bacterial growth. Racemic mixtures of the saturated 3-hydroxy fatty acids showed antifungal activity against different molds and yeasts with MICs between 10 and 100 micrograms ml-1.

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Year:  2003        PMID： 14660414      PMCID： PMC309954          DOI： 10.1128/AEM.69.12.7554-7557.2003

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  17 in total

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