| Literature DB >> 14643347 |
John L Kane1, Bradford H Hirth, Beirong Liang, Brian B Gourlie, Sharon Nahill, Gary Barsomian.
Abstract
Ureas of 5-aminopyrazole and 2-aminothiazole emerged as lead compounds from a high-throughput screen assaying the growth of Staphylococcus aureus. Structure-activity relationships were developed for each compound series. Several compounds were also tested for activity against drug resistant strains of S. aureus in vivo.Entities:
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Year: 2003 PMID： 14643347 DOI： 10.1016/j.bmcl.2003.09.013
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823