Literature DB >> 14602304

Mediastinitis after pediatric cardiac surgery: a 15-year experience at a single institution.

Tia A Tortoriello1, Jeffrey D Friedman, E Dean McKenzie, Charles D Fraser, Timothy F Feltes, Jessica Randall, Antonio R Mott.   

Abstract

BACKGROUND: The spectrum of sternal wound infections after cardiac surgery ranges from superficial infections to a deep sternal infection known as mediastinitis. Mediastinitis is a rare but clinically relevant source of postoperative morbidity and mortality in adult and pediatric patients after cardiac surgery.
METHODS: We retrospectively identified all patients diagnosed with mediastinitis after cardiac surgery from January 1987 to December 2002 (17 patients/7,616 surgeries = 0.2%). Demographic data, cardiac diagnosis, cardiac surgery, hospital length of stay, associated medical diagnosis, and surgical treatment for mediastinitis were collected.
RESULTS: Fifteen pediatric patients (age < 18 years) were diagnosed with mediastinitis (mean age at diagnosis 37.5 months, range 21 days to 17 years. The median postoperative day of diagnosis was 14 days (6 to 50 days). The most common organism was Staphylococcus species (n = 9). Six patients had an associated bacteremia. The median hospital length of stay for all patients was 42.5 days (range 16 to 163 days). The hospital mortality was 1 of 15 (6%). Each patient was treated with intravenous antibiotics; sternal debridement; and rectus abdominus flap reconstruction (n = 7), pectoralis muscle flap reconstruction (n = 3), omentum reconstruction (n = 1), or primary sternal closure (n = 4). Three patients have undergone redo-sternotomy with orthotopic heart transplantation, bidirectional cavopulmonary anastomosis, and replacement of a right ventricle to pulmonary artery homograft.
CONCLUSIONS: Timely diagnosis, aggressive sternal debridement, and liberal use of rotational muscle flaps can potentially minimize the morbidity and mortality in pediatric postoperative cardiac patients. Subsequent redo-sternotomy has not been problematic.

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Year:  2003        PMID: 14602304     DOI: 10.1016/s0003-4975(03)01025-7

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  12 in total

1.  Continuous infusion of nafcillin for sternal osteomyelitis in an infant after cardiac surgery.

Authors:  Chad A Knoderer; Jennifer L Morris; Elaine G Cox
Journal:  J Pediatr Pharmacol Ther       Date:  2010-01

2.  Mediastinitis in pediatric cardiac surgery: Prevention, diagnosis and treatment.

Authors:  Yves Durandy
Journal:  World J Cardiol       Date:  2010-11-26

3.  Successful Salvage of an Extracardiac Fontan in the Setting of Purulent Mediastinitis using Antibiotic-Impregnated Beads.

Authors:  Matthew T Coghill; Gonzalo A Wallis; Paul M Kirshbom; Thomas S Maxey
Journal:  J Pediatr Intensive Care       Date:  2018-02-06

4.  Major infection after pediatric cardiac surgery: a risk estimation model.

Authors:  Gregory M Barker; Sean M O'Brien; Karl F Welke; Marshall L Jacobs; Jeffrey P Jacobs; Daniel K Benjamin; Eric D Peterson; James Jaggers; Jennifer S Li
Journal:  Ann Thorac Surg       Date:  2010-03       Impact factor: 4.330

5.  Implementing a standardized perioperative antibiotic prophylaxis protocol for neonates undergoing cardiac surgery.

Authors:  Meghan T Murray; Rozelle Corda; Rebecca Turcotte; Emile Bacha; Lisa Saiman; Ganga Krishnamurthy
Journal:  Ann Thorac Surg       Date:  2014-07-16       Impact factor: 4.330

6.  Mediastinitis in pediatric cardiac surgery: treatment and cost-effectiveness in a low-income country.

Authors:  V L Vida; J Leon-Wyss; A Larrazabal; S Cruz; A R Castaneda
Journal:  Pediatr Cardiol       Date:  2007-03-05       Impact factor: 1.655

Review 7.  Extracardiac Complications in Intensive Care Units after Surgical Repair for Congenital Heart Disease: Imaging Review with a Focus on Ultrasound and Radiography.

Authors:  Takahiro Hosokawa; Saki Shibuki; Yutaka Tanami; Yumiko Sato; Yoshihiro Ko; Koji Nomura; Eiji Oguma
Journal:  J Pediatr Intensive Care       Date:  2020-09-09

8.  Perioperative antibiotics in pediatric cardiac surgery: protocol for a systematic review.

Authors:  Vijay Anand; Angela Bates; Robin Featherstone; Srinivas Murthy
Journal:  Syst Rev       Date:  2017-05-30

9.  Volumetric Computed Tomography Angiography in the Evaluation of Mediastinal Fluid Collections following Congenital Cardiac Surgery.

Authors:  Arno A W Roest; Joost Roelofs; Mark G Hazekamp; Marry E B Rijlaarsdam; Jacob Geleijns; Lucia J M Kroft
Journal:  Case Rep Pediatr       Date:  2013-01-28

10.  Superficial and deep sternal wound infection after more than 9000 coronary artery bypass graft (CABG): incidence, risk factors and mortality.

Authors:  Abbas Salehi Omran; Abbasali Karimi; S Hossein Ahmadi; Setareh Davoodi; Mehrab Marzban; Namvar Movahedi; Kyomars Abbasi; Mohammad Ali Boroumand; Saeed Davoodi; Naghmeh Moshtaghi
Journal:  BMC Infect Dis       Date:  2007-09-23       Impact factor: 3.090

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