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Literature DB >> 22477793

Continuous infusion of nafcillin for sternal osteomyelitis in an infant after cardiac surgery.

Chad A Knoderer¹, Jennifer L Morris, Elaine G Cox.

Abstract

We report the use of the continuous infusion of nafcillin for the treatment of an infant who had methicillinsusceptible Staphylococcus aureus sternal osteomyelitis not responsive to traditional nafcillin dosing. The patient was successfully treated with surgical debridement and the continuous infusion of nafcillin. To our knowledge, this is the first report describing the successful use of the continuous infusion of nafcillin to treat an infant who had sternal osteomyelitis after cardiac surgery.

Entities: Chemical Disease Species

Year: 2010 PMID： 22477793 PMCID： PMC3017409

Source DB: PubMed Journal: J Pediatr Pharmacol Ther ISSN： 1551-6776

25 in total

1. Hypothermia as a risk factor for pediatric cardiothoracic surgical site infection.

Authors: H B McAnally; G R Cutter; A J Ruttenber; D Clarke; J K Todd
Journal: Pediatr Infect Dis J Date: 2001-04 Impact factor: 2.129

Review 2. Antimicrobial prophylaxis for surgery: an advisory statement from the National Surgical Infection Prevention Project.

Authors: Dale W Bratzler; Peter M Houck
Journal: Am J Surg Date: 2005-04 Impact factor: 2.565

3. Continuous antibiotic infusion for salvage therapy of partially implanted central venous catheter tunnel infections due to staphylococci.

Authors: M Giacchino; S Bezzio; N Chiapello; P Saracco; F Fagioli; I Caviglia; C Moroni; E Castagnola
Journal: Pediatr Blood Cancer Date: 2007-12 Impact factor: 3.167

4. Etiology and management of pediatric chylothorax.

Authors: M Beghetti; G La Scala; D Belli; P Bugmann; A Kalangos; C Le Coultre
Journal: J Pediatr Date: 2000-05 Impact factor: 4.406

5. Risk factors for sternal wound and other infections in pediatric cardiac surgery patients.

Authors: P A Mehta; C K Cunningham; C B Colella; G Alferis; L B Weiner
Journal: Pediatr Infect Dis J Date: 2000-10 Impact factor: 2.129

6. Continuous infusion of ceftazidime with a portable pump is as effective as thrice-a-day bolus in cystic fibrosis children.

Authors: I Rappaz; L A Decosterd; J Bille; M Pilet; N Bélaz; M Roulet
Journal: Eur J Pediatr Date: 2000-12 Impact factor: 3.183

Review 7. Primary sternal osteomyelitis: a case series and review of the literature.

Authors: Manasvi Upadhyaya; Anthony Keil; Sven Thonell; Jillian Orford; David Burgner
Journal: J Pediatr Surg Date: 2005-10 Impact factor: 2.545

Review 8. Continuous infusion of beta-lactams.

Authors: Johan W Mouton; Alexander A Vinks
Journal: Curr Opin Crit Care Date: 2007-10 Impact factor: 3.687

Continuous infusion of nafcillin for sternal osteomyelitis in an infant after cardiac surgery.

1. Hypothermia as a risk factor for pediatric cardiothoracic surgical site infection.

Review 2. Antimicrobial prophylaxis for surgery: an advisory statement from the National Surgical Infection Prevention Project.

3. Continuous antibiotic infusion for salvage therapy of partially implanted central venous catheter tunnel infections due to staphylococci.

4. Etiology and management of pediatric chylothorax.

5. Risk factors for sternal wound and other infections in pediatric cardiac surgery patients.

6. Continuous infusion of ceftazidime with a portable pump is as effective as thrice-a-day bolus in cystic fibrosis children.

Review 7. Primary sternal osteomyelitis: a case series and review of the literature.

Review 8. Continuous infusion of beta-lactams.

9. Median sternotomy wound infections in children.

10. Mediastinitis after pediatric cardiac surgery: a 15-year experience at a single institution.

1. Clinical Outcomes With Continuous Nafcillin Infusions in Children.

2. Optimized antimicrobial dosing strategies: a survey of pediatric hospitals.