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Literature DB >> 14600122

Sputum examination for early detection of lung cancer.

Abstract

Conventional sputum cytology can be used for the detection of lung cancer, but has shown a low yield in prospective screening trials. This review focuses on the technical aspects relevant to the outcome of DNA and image analysis in sputum. Published articles are discussed in the light of the technical background. Recent developments in DNA analysis and nuclear image analysis show a clear potential to improve or refine diagnosis beyond that achieved with conventional sputum cytology examination. The challenge for future studies in DNA and nuclear analysis of sputum is to ensure high levels of quality control and to confirm these initial encouraging results.

Entities: Disease

Mesh：

Substances：

Year: 2003 PMID： 14600122 PMCID： PMC1770101 DOI： 10.1136/jcp.56.11.805

Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411

73 in total

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Journal: Cancer Res Date: 1996-05-15 Impact factor: 12.701

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Journal: Acta Cytol Date: 1999 Jul-Aug Impact factor: 2.319

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Journal: Arch Intern Med Date: 1994-05-09

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Journal: Am J Respir Crit Care Med Date: 1996-01 Impact factor: 21.405

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29 in total

1. Clinical Utility of Chromosomal Aneusomy in Individuals at High Risk of Lung Cancer.

Authors: Anna E Barón; Severine Kako; William J Feser; Heather Malinowski; Daniel Merrick; Kavita Garg; Stephen Malkoski; Shannon Pretzel; Jill M Siegfried; Wilbur A Franklin; York Miller; Holly J Wolf; Marileila Varella-Garcia
Journal: J Thorac Oncol Date: 2017-06-19 Impact factor: 15.609

2. Detection and quantification of rare mutations with massively parallel sequencing.

Authors: Isaac Kinde; Jian Wu; Nick Papadopoulos; Kenneth W Kinzler; Bert Vogelstein
Journal: Proc Natl Acad Sci U S A Date: 2011-05-17 Impact factor: 11.205

3. Fluorescent metal nanoshell probe to detect single miRNA in lung cancer cell.

Authors: Jian Zhang; Yi Fu; Yuping Mei; Feng Jiang; Joseph R Lakowicz
Journal: Anal Chem Date: 2010-06-01 Impact factor: 6.986

4. Identification of ENO1 as a potential sputum biomarker for early-stage lung cancer by shotgun proteomics.

Authors: Lei Yu; Jun Shen; Kaiissar Mannoor; Maria Guarnera; Feng Jiang
Journal: Clin Lung Cancer Date: 2014-06-03 Impact factor: 4.785

5. Expression profile of Oct-4 lung cancer-specific marker prior and subsequent to a salirasib treatment regime.

Authors: Xiang Ao; Jie Zhou; Hong Ling Liang; Ming Jiang; Hong Sheng Li
Journal: Oncol Lett Date: 2017-09-01 Impact factor: 2.967

6. Fluorescence-assisted cytological testing (FACT): Ex Vivo viral method for enhancing detection of rare cancer cells in body fluids.

Authors: Prasad S Adusumilli; Sepideh Gholami; Yun Shin Chun; Michael Mullerad; Mei Ki Chan; Zhenkun Yu; Leah Ben-Porat; Valerie W Rusch; Yuman Fong
Journal: Mol Med Date: 2011-04-08 Impact factor: 6.354