| Literature DB >> 14592505 |
Andrew Baxter1, Janice Bent, Keith Bowers, Martin Braddock, Steve Brough, Malbinder Fagura, Mandy Lawson, Tom McInally, Mike Mortimore, Mark Robertson, Richard Weaver, Peter Webborn.
Abstract
A Hit-to-Lead optimisation programme was carried out on the adamantane high throughput screening hit 1 resulting in the discovery of a number of potent P2X(7) antagonists.Entities:
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Year: 2003 PMID： 14592505 DOI： 10.1016/j.bmcl.2003.08.034
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823