Literature DB >> 14592171

The role of obesity in the increased prevalence of obstructive sleep apnea syndrome in patients with polycystic ovarian syndrome.

Mira Gopal1, Stephen Duntley, Matt Uhles, Hrayr Attarian.   

Abstract

OBJECTIVES: To determine the prevalence of obstructive sleep apnea syndrome (OSAS) in a population of premenopausal women with polycystic ovarian syndrome (PCOS) and to study the impact of obesity on the increased prevalence of OSAS in this population.
METHODS: Twenty-three premenopausal women with definite PCOS, and no prior diagnosis of a sleep disorder, were recruited from gynecology clinics. An investigator interviewed them, for symptoms of excessive sleepiness, their body mass index (BMI) was calculated, and they underwent overnight polysomnography.
RESULTS: Sixteen of 23 (69.6%) met criteria for OSAS. Five were treated with continuous positive airway pressure. Confidence interval was 47.7-84.5%. An increased respiratory disturbance index (RDI) did not correlate with higher BMI.
CONCLUSIONS: OSAS is significantly more prevalent in this population than in a population of obese women. There was no correlation between obesity and severity of the OSAS. Obesity is not the cause of this increased prevalence of OSAS in a population of women with PCOS.

Entities:  

Year:  2002        PMID: 14592171     DOI: 10.1016/s1389-9457(02)00033-3

Source DB:  PubMed          Journal:  Sleep Med        ISSN: 1389-9457            Impact factor:   3.492


  30 in total

Review 1.  [Comorbidities and complications of adiposis].

Authors:  C Dieterle; R Landgraf
Journal:  Internist (Berl)       Date:  2006-02       Impact factor: 0.743

2.  Sleep Apnea and its association with the Stress System, Inflammation, Insulin Resistance and Visceral Obesity.

Authors:  G Trakada; G Chrousos; S Pejovic; A Vgontzas
Journal:  Sleep Med Clin       Date:  2007-06

3.  Long term health consequences of polycystic ovarian syndrome: a review analysis.

Authors:  A Daniilidis; K Dinas
Journal:  Hippokratia       Date:  2009-04       Impact factor: 0.471

4.  The impact of insulin resistance and hyperandrogenemia on polysomnographic variables in obese adolescents with polycystic ovarian syndrome.

Authors:  Gideon de Sousa; Bernhard Schlüter; Dirk Buschatz; Thomas Menke; Eckardt Trowitzsch; Werner Andler; Thomas Reinehr
Journal:  Sleep Breath       Date:  2011-01-08       Impact factor: 2.816

5.  Risk of obstructive sleep apnea in obese and nonobese women with polycystic ovary syndrome and healthy reproductively normal women.

Authors:  Babak Mokhlesi; Bert Scoccia; Theodore Mazzone; Susan Sam
Journal:  Fertil Steril       Date:  2012-01-20       Impact factor: 7.329

6.  Treatment of obstructive sleep apnea improves cardiometabolic function in young obese women with polycystic ovary syndrome.

Authors:  Esra Tasali; Florian Chapotot; Rachel Leproult; Harry Whitmore; David A Ehrmann
Journal:  J Clin Endocrinol Metab       Date:  2010-12-01       Impact factor: 5.958

7.  Longitudinal analyses of polysomnographic variables, serum androgens, and parameters of glucose metabolism in obese adolescents with polycystic ovarian syndrome.

Authors:  Gideon de Sousa; Bernhard Schlüter; Thomas Menke; Eckardt Trowitzsch; Werner Andler; Thomas Reinehr
Journal:  Sleep Breath       Date:  2011-11-20       Impact factor: 2.816

Review 8.  Obstructive sleep apnea and metabolic dysfunction in polycystic ovary syndrome.

Authors:  Katie Nitsche; David A Ehrmann
Journal:  Best Pract Res Clin Endocrinol Metab       Date:  2010-10       Impact factor: 4.690

Review 9.  Obstructive sleep apnea and the metabolic syndrome: The road to clinically-meaningful phenotyping, improved prognosis, and personalized treatment.

Authors:  Jordan Gaines; Alexandros N Vgontzas; Julio Fernandez-Mendoza; Edward O Bixler
Journal:  Sleep Med Rev       Date:  2018-09-03       Impact factor: 11.609

10.  A comparison of polysomnographic variables between obese adolescents with polycystic ovarian syndrome and healthy, normal-weight and obese adolescents.

Authors:  Gideon de Sousa; Bernhard Schlüter; Dirk Buschatz; Thomas Menke; Eckardt Trowitzsch; Werner Andler; Thomas Reinehr
Journal:  Sleep Breath       Date:  2009-07-08       Impact factor: 2.816

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