OBJECTIVE: To study the risk for obstructive sleep apnea (OSA) in a group of nonobese and obese polycystic ovary syndrome (PCOS) and control women. DESIGN: Prospective study. SETTING: Academic tertiary care medical center. PATIENT(S): Forty-four women with PCOS and 34 control women. INTERVENTION(S): All of the women completed the Berlin questionnaire for assessment of OSA risk. MAIN OUTCOME MEASURE(S): All of the women underwent fasting determination of androgens, glucose, and insulin. RESULT(S): Women with PCOS were more obese compared with control women. However, there were no differences in BMI once subjects were divided into nonobese (PCOS: n = 17; control: n = 26) and obese (PCOS: n = 27; control: n = 8) groups. Women with PCOS had higher prevalence of high-risk OSA compared with control women (47% vs. 15%). However, none of the nonobese PCOS and control women screened positively for high-risk OSA. Among the obese group, the risk did not differ between groups (77% vs. 63%). CONCLUSION(S): Our findings indicate that even though the risk for OSA in PCOS is high, it is related to the high prevalence of severe obesity. The risk for OSA among nonobese women with PCOS is very low. However, our findings are limited by lack of polysomnographic confirmation of OSA.
OBJECTIVE: To study the risk for obstructive sleep apnea (OSA) in a group of nonobese and obese polycystic ovary syndrome (PCOS) and control women. DESIGN: Prospective study. SETTING: Academic tertiary care medical center. PATIENT(S): Forty-four women with PCOS and 34 control women. INTERVENTION(S): All of the women completed the Berlin questionnaire for assessment of OSA risk. MAIN OUTCOME MEASURE(S): All of the women underwent fasting determination of androgens, glucose, and insulin. RESULT(S): Women with PCOS were more obese compared with control women. However, there were no differences in BMI once subjects were divided into nonobese (PCOS: n = 17; control: n = 26) and obese (PCOS: n = 27; control: n = 8) groups. Women with PCOS had higher prevalence of high-risk OSA compared with control women (47% vs. 15%). However, none of the nonobese PCOS and control women screened positively for high-risk OSA. Among the obese group, the risk did not differ between groups (77% vs. 63%). CONCLUSION(S): Our findings indicate that even though the risk for OSA in PCOS is high, it is related to the high prevalence of severe obesity. The risk for OSA among nonobese women with PCOS is very low. However, our findings are limited by lack of polysomnographic confirmation of OSA.
Authors: Gideon de Sousa; Bernhard Schlüter; Thomas Menke; Eckardt Trowitzsch; Werner Andler; Thomas Reinehr Journal: J Sleep Res Date: 2010-12-29 Impact factor: 3.981
Authors: Esther Quintana-Gallego; Carmen Carmona-Bernal; Francisco Capote; Angeles Sánchez-Armengol; Georgina Botebol-Benhamou; Juan Polo-Padillo; Jóse Castillo-Gómez Journal: Respir Med Date: 2004-10 Impact factor: 3.415
Authors: Sinziana Seicean; H Lester Kirchner; Daniel J Gottlieb; Naresh M Punjabi; Helaine Resnick; Mark Sanders; Rohit Budhiraja; Mendel Singer; Susan Redline Journal: Diabetes Care Date: 2008-02-11 Impact factor: 19.112
Authors: Renae C Fernandez; Vivienne M Moore; Emer M Van Ryswyk; Tamara J Varcoe; Raymond J Rodgers; Wendy A March; Lisa J Moran; Jodie C Avery; R Doug McEvoy; Michael J Davies Journal: Nat Sci Sleep Date: 2018-02-01