| Literature DB >> 14576141 |
Stefano P Bachmann1, Gordon Ramage, Kacy VandeWalle, Thomas F Patterson, Brian L Wickes, José L López-Ribot.
Abstract
Candida biofilms display increased resistance to most antifungal agents. We have evaluated the efficacy of combinations of fluconazole (FLC), amphotericin B, and caspofungin (CSP) against Candida albicans biofilms in vitro. Indifference was observed for all the combinations of paired antifungal agents when a checkerboard titration method was used. Time-kill experiments revealed an antagonistic effect of high FLC doses with CSP.Entities:
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Year: 2003 PMID: 14576141 PMCID: PMC253764 DOI: 10.1128/AAC.47.11.3657-3659.2003
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191