| Literature DB >> 14566346 |
Pamela J Kling1, John J Hutter.
Abstract
Necrotizing enterocolitis (NEC), the most common surgical emergency in newborns, remains a therapeutic challenge for clinicians. The hematological manifestations associated with NEC were first described 25 years ago. This review discusses current knowledge of the pathophysiology involved in disturbances in megakaryocytopoiesis, coagulation, leukopoiesis, and erythropoiesis that accompany the clinical entity NEC. The discussion includes current understanding of and potential strategies for treating the hematopoietic disturbances that occur secondary to NEC.Entities:
Mesh：
Year: 2003 PMID： 14566346 DOI： 10.1038/sj.jp.7210983
Source DB: PubMed Journal: J Perinatol ISSN： 0743-8346 Impact factor: 2.521