Literature DB >> 14561932

Genetic influences on frontal brain function: WCST performance in twins.

Andrey P Anokhin1, Andrew C Heath, Angela Ralano.   

Abstract

The Wisconsin Card Sorting Test (WCST) is one of the most widely used assessments of executive functioning related to prefrontal cortex. However, little is known about genetic and environmental determinants of individual differences in WCST performance. This study assessed heritability of standard WCST scores in a sample of 168 young female twins including 58 monozygotic and 25 dizygotic pairs. Several WSCT indices, including the number and percentage of errors, the number of perseverative responses, and the number and percent of perseverative errors, showed significant heritability ranging from 37 to 46%. The results suggest that selected aspects of frontal executive functioning measured by the WCST are moderately influenced by genetic factors.

Mesh：

Year:  2003        PMID： 14561932     DOI： 10.1097/00001756-200310270-00019

Source DB:  PubMed          Journal:  Neuroreport        ISSN： 0959-4965            Impact factor:   1.837


  20 in total

1.  Phenotypic and genetic analyses of the Wisconsin Card Sort.

Authors:  Detre A Godinez; Naomi P Friedman; Soo Hyun Rhee; Akira Miyake; John K Hewitt
Journal:  Behav Genet       Date:  2011-09-28       Impact factor: 2.805

Review 2.  Neurocognitive function as an endophenotype for genetic studies of bipolar affective disorder.

Authors:  Jonathan B Savitz; Mark Solms; Rajkumar S Ramesar
Journal:  Neuromolecular Med       Date:  2005       Impact factor: 3.843

Review 3.  Cognitive deficits in unaffected first-degree relatives of schizophrenia patients: a meta-analytic review of putative endophenotypes.

Authors:  Beth E Snitz; Angus W Macdonald; Cameron S Carter
Journal:  Schizophr Bull       Date:  2005-09-15       Impact factor: 9.306

4.  Individual differences in executive functions are almost entirely genetic in origin.

Authors:  Naomi P Friedman; Akira Miyake; Susan E Young; John C DeFries; Robin P Corley; John K Hewitt
Journal:  J Exp Psychol Gen       Date:  2008-05

5.  Reaction time, inhibition, working memory and 'delay aversion' performance: genetic influences and their interpretation.

Authors:  Jonna Kuntsi; Hannah Rogers; Greer Swinard; Norbert Börger; Jaap van der Meere; Fruhling Rijsdijk; Philip Asherson
Journal:  Psychol Med       Date:  2006-08-02       Impact factor: 7.723

6.  Single nucleotide polymorphism heritability and differential patterns of genetic overlap between inattention and four neurocognitive factors in youth.

Authors:  Lauren Micalizzi; Leslie A Brick; Marisa E Marraccini; Chelsie E Benca-Bachman; Rohan H C Palmer; Valerie S Knopik
Journal:  Dev Psychopathol       Date:  2021-02

7.  An update on the Florida State Twin Registry.

Authors:  Jeanette E Taylor; Sara A Hart; Amy J Mikolajewski; Christopher Schatschneider
Journal:  Twin Res Hum Genet       Date:  2012-10-15       Impact factor: 1.587

8.  Clustering by neurocognition for fine mapping of the schizophrenia susceptibility loci on chromosome 6p.

Authors:  S-H Lin; C-M Liu; Y-L Liu; C Shen-Jang Fann; P-C Hsiao; J-Y Wu; S-I Hung; C-H Chen; H-M Wu; Y-S Jou; S K Liu; T J Hwang; M H Hsieh; C-C Chang; W-C Yang; J-J Lin; F H-C Chou; S V Faraone; M T Tsuang; H-G Hwu; W J Chen
Journal:  Genes Brain Behav       Date:  2009-07-21       Impact factor: 3.449

9.  A marginal rank-based inverse normal transformation approach to comparing multiple clinical trial endpoints.

Authors:  Xiaoyu Cai; Huiyun Li; Aiyi Liu
Journal:  Stat Med       Date:  2016-03-14       Impact factor: 2.373

10.  Heritability of Trail Making Test performance in multiplex schizophrenia families: implications for the search for an endophenotype.

Authors:  Raúl Mendoza Quiñones; Yuranny Cabral Calderín; Mayelin Domínguez; Tania M Bravo; Adnelys Reyes Berazaín; Alexander García; Antonio Caballero; Migdyrai Martín Reyes
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2009-04-28       Impact factor: 5.270
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