Literature DB >> 14552749

Novel chromene derivatives as TNF-alpha inhibitors.

Jie-Fei Cheng1, Akira Ishikawa, Yoshinori Ono, Thomas Arrhenius, Alex Nadzan.   

Abstract

A novel series of chromene-based TNF-alpha inhibitors is described. These chromene derivatives inhibit bacterial lipopolysaccharide (LPS) stimulated production of TNF-alpha from human peripheral blood mononuclear cells (PBMC). Additionally, these compounds inhibit NF-kB mediated transcription activation.

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Year:  2003        PMID： 14552749     DOI： 10.1016/j.bmcl.2003.08.025

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  8 in total

1.  Structure-activity relationships and molecular docking studies of chromene and chromene based azo chromophores: A novel series of potent antimicrobial and anticancer agents.

Authors:  Tarek H Afifi; Rawda M Okasha; Hany E A Ahmed; Janez Ilaš; Tarek Saleh; Alaa S Abd-El-Aziz
Journal:  EXCLI J       Date:  2017-06-19       Impact factor: 4.068

2.  Crystal structures and conformational analyses of three pyranochromene derivatives.

Authors:  K Swaminathan; K Sethusankar; G Siva Kumar; M Bakthadoss
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2015-07-15

3.  Crystal structure of 3-amino-1-(4-meth-oxy-phen-yl)-1H-benzo[f]chromene-2-carbo-nitrile.

Authors:  Shaaban K Mohamed; Peter N Horton; Mehmet Akkurt; Sabry H H Younes; Mustafa R Albayati
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2015-06-13

4.  Green Protocol for the Novel Synthesis of Thiochromeno[4,3-b]pyridine and Chromeno[4,3-b]pyridine Derivatives Utilizing a High-Pressure System.

Authors:  Haider Behbehani; Kamal M Dawood; Fatemah A Aryan; Hamada Mohamed Ibrahim
Journal:  ACS Omega       Date:  2021-11-30

5.  One-pot facile and mild construction of densely functionalized pyrimidines in water via consecutive C-C and C-S bonds formation.

Authors:  Pramod K Sahu; Praveen K Sahu; Manvendra S Kaurav; Mouslim Messali; Saud M Almutairi; Puran L Sahu; Dau D Agarwal
Journal:  RSC Adv       Date:  2018-10-03       Impact factor: 3.361

6.  A PANI-Fe3O4@ZnO nanocomposite: a magnetically separable and applicable catalyst for the synthesis of chromeno-pyrido[d]pyrimidine derivatives.

Authors:  Fatemeh Chaghari-Farahani; Shahrzad Abdolmohammadi; Reza Kia-Kojoori
Journal:  RSC Adv       Date:  2020-04-21       Impact factor: 4.036

7.  Pharmacological Evaluation and Docking Studies of 3-Thiadiazolyl- and Thioxo-1,2,4-triazolylcoumarin Derivatives as Cholinesterase Inhibitors.

Authors:  Ahsan Raza; Aamer Saeed; Aliya Ibrar; Muhammad Muddassar; Aftab Ahmed Khan; Jamshed Iqbal
Journal:  ISRN Pharmacol       Date:  2012-08-16

8.  QSAR and docking studies on capsazepine derivatives for immunomodulatory and anti-inflammatory activity.

Authors:  Aparna Shukla; Pooja Sharma; Om Prakash; Monika Singh; Komal Kalani; Feroz Khan; Dnyaneshwar Umrao Bawankule; Suaib Luqman; Santosh Kumar Srivastava
Journal:  PLoS One       Date:  2014-07-08       Impact factor: 3.240
  8 in total

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