Literature DB >> 1454831

Spermine and spermidine protection of plasmid DNA against single-strand breaks induced by singlet oxygen.

A U Khan1, P Di Mascio, M H Medeiros, T Wilson.   

Abstract

Oxidative damage to DNA induced by singlet molecular oxygen (1O2*) includes single-strand breaks, which the biologically occurring 1O2* quenchers spermine and spermidine are shown to prevent. These polyamines at a physiological concentration (10 mM) reduce the percentage of the open circular form of pBR322 plasmid DNA, which is generated at the expense of the native supercoiled form when the plasmids are incubated with a chemical source of 1O2*, the water-soluble endoperoxide of 3,3'-(1,4-naphthylidene)dipropionate. Spermine and spermidine can be expected to protect DNA against other damaging effects of 1O2*.

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Year:  1992        PMID： 1454831      PMCID： PMC50564          DOI： 10.1073/pnas.89.23.11428

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  7 in total

1.  Singlet oxygen induced single-strand breaks in plasmid pBR322 DNA: the enhancing effect of thiols.

Authors:  T P Devasagayam; P Di Mascio; S Kaiser; H Sies
Journal:  Biochim Biophys Acta       Date:  1991-03-26

2.  Formation of 8-hydroxy(deoxy)guanosine and generation of strand breaks at guanine residues in DNA by singlet oxygen.

Authors:  T P Devasagayam; S Steenken; M S Obendorf; W A Schulz; H Sies
Journal:  Biochemistry       Date:  1991-06-25       Impact factor: 3.162

3.  Singlet molecular oxygen causes loss of biological activity in plasmid and bacteriophage DNA and induces single-strand breaks.

Authors:  P Di Mascio; H Wefers; H P Do-Thi; M V Lafleur; H Sies
Journal:  Biochim Biophys Acta       Date:  1989-03-01

4.  A proposed function for spermine and spermidine: protection of replicating DNA against damage by singlet oxygen.

Authors:  A U Khan; Y H Mei; T Wilson
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-01       Impact factor: 11.205

5.  Singlet oxygen induces frank strand breaks as well as alkali- and piperidine-labile sites in supercoiled plasmid DNA.

Authors:  E R Blazek; J G Peak; M J Peak
Journal:  Photochem Photobiol       Date:  1989-05       Impact factor: 3.421

6.  Singlet oxygen induced DNA damage and mutagenicity in a single-stranded SV40-based shuttle vector.

Authors:  D T Ribeiro; C Madzak; A Sarasin; P Di Mascio; H Sies; C F Menck
Journal:  Photochem Photobiol       Date:  1992-01       Impact factor: 3.421

Review 7.  Biological consequences associated with DNA oxidation mediated by singlet oxygen.

Authors:  J Piette
Journal:  J Photochem Photobiol B       Date:  1991-12       Impact factor: 6.252
  7 in total
  27 in total

1.  Radiation protection following nuclear power accidents: a survey of putative mechanisms involved in the radioprotective actions of taurine during and after radiation exposure.

Authors:  Olav Albert Christophersen
Journal:  Microb Ecol Health Dis       Date:  2012-02-01

2.  Murine macrophage transcriptional responses to Bacillus anthracis infection and intoxication.

Authors:  Nicholas H Bergman; Karla D Passalacqua; Renee Gaspard; Lynne M Shetron-Rama; John Quackenbush; Philip C Hanna
Journal:  Infect Immun       Date:  2005-02       Impact factor: 3.441

3.  Functional characterization of seven γ-Glutamylpolyamine synthetase genes and the bauRABCD locus for polyamine and β-Alanine utilization in Pseudomonas aeruginosa PAO1.

Authors:  Xiangyu Yao; Weiqing He; Chung-Dar Lu
Journal:  J Bacteriol       Date:  2011-05-27       Impact factor: 3.490

4.  The natural polyamine spermine functions directly as a free radical scavenger.

Authors:  H C Ha; N S Sirisoma; P Kuppusamy; J L Zweier; P M Woster; R A Casero
Journal:  Proc Natl Acad Sci U S A       Date:  1998-09-15       Impact factor: 11.205

5.  Arginine catabolic mobile element encoded speG abrogates the unique hypersensitivity of Staphylococcus aureus to exogenous polyamines.

Authors:  Gauri S Joshi; Jeffrey S Spontak; David G Klapper; Anthony R Richardson
Journal:  Mol Microbiol       Date:  2011-09-08       Impact factor: 3.501

6.  Hydroxyl radical scavenging and singlet oxygen quenching properties of polyamines.

Authors:  Kumuda C Das; Hara P Misra
Journal:  Mol Cell Biochem       Date:  2004-07       Impact factor: 3.396

7.  Disruption of putrescine biosynthesis in Shewanella oneidensis enhances biofilm cohesiveness and performance in Cr(VI) immobilization.

Authors:  Yuanzhao Ding; Ni Peng; Yonghua Du; Lianghui Ji; Bin Cao
Journal:  Appl Environ Microbiol       Date:  2013-12-20       Impact factor: 4.792

8.  A proposed function for spermine and spermidine: protection of replicating DNA against damage by singlet oxygen.

Authors:  A U Khan; Y H Mei; T Wilson
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-01       Impact factor: 11.205

9.  Effect of Sex on Biomarker Response in a Mouse Model of the Hematopoietic Acute Radiation Syndrome.

Authors:  Jace W Jones; Jenna Alloush; Rajendran Sellamuthu; Hui Lin Chua; Thomas J MacVittie; Christie M Orschell; Maureen A Kane
Journal:  Health Phys       Date:  2019-04       Impact factor: 1.316

10.  Transcriptome analysis of agmatine and putrescine catabolism in Pseudomonas aeruginosa PAO1.

Authors:  Han Ting Chou; Dong-Hyeon Kwon; Mohamed Hegazy; Chung-Dar Lu
Journal:  J Bacteriol       Date:  2008-01-11       Impact factor: 3.490
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