Literature DB >> 14505668

Lupane triterpenes and derivatives with antiviral activity.

L A Baltina1, O B Flekhter, L R Nigmatullina, E I Boreko, N I Pavlova, S N Nikolaeva, O V Savinova, G A Tolstikov.   

Abstract

Betulin and betulinic acid have been modified at the C-3 and C-28 positions and the antiviral activity of derivatives has been evaluated in vitro. It was found that simple modifications of the parent structure of lupane triterpenes produced highly effective agents against influenza A and herpes simplex type 1 viruses.

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Year:  2003        PMID： 14505668     DOI： 10.1016/s0960-894x(03)00714-5

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  17 in total

1.  Study of the betulin molecule in a water environment; ab initio and molecular simulation calculations.

Authors:  Miroslav Pospíšil; Petr Kovář; Robert Vácha; Michal Svoboda
Journal:  J Mol Model       Date:  2011-05-03       Impact factor: 1.810

2.  In vitro studies on protective effect of Glycyrrhiza glabra root extracts against cadmium-induced genetic and oxidative damage in human lymphocytes.

Authors:  Ebubekir Dirican; Hasan Turkez
Journal:  Cytotechnology       Date:  2013-01-17       Impact factor: 2.058

3.  Hypericum lanceolatum (Hypericaceae) as a potential source of new anti-malarial agents: a bioassay-guided fractionation of the stem bark.

Authors:  Denis Zofou; Théodora K Kowa; Hippolyte K Wabo; Moses N Ngemenya; Pierre Tane; Vincent P K Titanji
Journal:  Malar J       Date:  2011-06-17       Impact factor: 2.979

Review 4.  Toxicity of ochratoxin a and its modulation by antioxidants: a review.

Authors:  Valeria Sorrenti; Claudia Di Giacomo; Rosaria Acquaviva; Ignazio Barbagallo; Matteo Bognanno; Fabio Galvano
Journal:  Toxins (Basel)       Date:  2013-10-11       Impact factor: 4.546

5.  Selective binding modes and allosteric inhibitory effects of lupane triterpenes on protein tyrosine phosphatase 1B.

Authors:  Tiantian Jin; Haibo Yu; Xu-Feng Huang
Journal:  Sci Rep       Date:  2016-02-11       Impact factor: 4.379

Review 6.  Compounds with anti-influenza activity: present and future of strategies for the optimal treatment and management of influenza. Part II: Future compounds against influenza virus.

Authors:  R Gasparini; D Amicizia; P L Lai; N L Bragazzi; D Panatto
Journal:  J Prev Med Hyg       Date:  2014-12

7.  Evaluation of A-azepano-triterpenoids and related derivatives as antimicrobial and antiviral agents.

Authors:  Oxana Kazakova; Elena Tret'yakova; Dmitry Baev
Journal:  J Antibiot (Tokyo)       Date:  2021-07-12       Impact factor: 2.649

8.  Phytochemical analysis and Enzyme Inhibition Assay of Aerva javanica for Ulcer.

Authors:  Abdul Wajid Khan; Saleem Jan; Shaista Parveen; Rahmat Ali Khan; Asma Saeed; Abdul Jabbar Tanveer; Anwar Ali Shad
Journal:  Chem Cent J       Date:  2012-07-31       Impact factor: 4.215

Review 9.  The role of triterpenes in the management of diabetes mellitus and its complications.

Authors:  J Nazaruk; M Borzym-Kluczyk
Journal:  Phytochem Rev       Date:  2014-06-24       Impact factor: 5.374

10.  The effect of 3β, 6β, 16β-trihydroxylup-20(29)-ene lupane compound isolated from Combretum leprosum Mart. on peripheral blood mononuclear cells.

Authors:  Fabianne Lacouth-Silva; Caroline V Xavier; Sulamita da S Setúbal; Adriana S Pontes; Neriane M Nery; Onassis Boeri de Castro; Carla F C Fernandes; Eduardo R Honda; Fernando B Zanchi; Leonardo A Calderon; Rodrigo G Stábeli; Andreimar M Soares; Izaltina Silva-Jardim; Valdir A Facundo; Juliana P Zuliani
Journal:  BMC Complement Altern Med       Date:  2015-11-25       Impact factor: 3.659
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