| Literature DB >> 14504329 |
S Nishino1, T Kanbayashi, N Fujiki, M Uchino, B Ripley, M Watanabe, G J Lammers, H Ishiguro, S Shoji, Y Nishida, S Overeem, I Toyoshima, Y Yoshida, T Shimizu, S Taheri, E Mignot.
Abstract
CSF hypocretin-1 was measured in 28 Guillain-Barré syndrome (GBS), 12 Miller-Fisher syndrome, 12 chronic inflammatory demyelinating polyneuropathy (CIDP), and 48 control subjects. Seven GBS subjects had undetectably low hypocretin-1 levels (<100 pg/mL). Hypocretin-1 levels were moderately reduced in an additional 11 GBS, 5 Miller-Fisher syndrome, and 1 CIDP subject. Low levels in GBS occurred early in the disease and were associated with upper CNS level abnormalities.Entities:
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Year: 2003 PMID: 14504329 DOI: 10.1212/01.wnl.0000081049.14098.50
Source DB: PubMed Journal: Neurology ISSN: 0028-3878 Impact factor: 9.910