Literature DB >> 1447155

A second gene for a secreted aspartate proteinase in Candida albicans.

R J Wright1, A Carne, A D Hieber, I L Lamont, G W Emerson, P A Sullivan.   

Abstract

The gene (PRA11) encoding a secreted aspartate proteinase of Candida albicans has been cloned and sequenced. The nucleotide and deduced amino acid sequences of PRA11 are 77 and 73% identical, respectively, with the reported sequences of PRA10 also cloned from C. albicans. Southern analyses indicated that the genome of each strain examined (ATCC 10231 and ATCC 10261) contains PRA10 and PRA11. Northern (RNA) analyses showed that PRA11 was expressed at a much higher level than was PRA10 when secretion of the proteinase by strain ATCC 10261 was induced with albumin.

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Year:  1992        PMID: 1447155      PMCID: PMC207505          DOI: 10.1128/jb.174.23.7848-7853.1992

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  21 in total

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Journal:  Sabouraudia       Date:  1965-10

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Authors:  R Rüchel
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Journal:  Sabouraudia       Date:  1982-09
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  22 in total

1.  Misexpression of the opaque-phase-specific gene PEP1 (SAP1) in the white phase of Candida albicans confers increased virulence in a mouse model of cutaneous infection.

Authors:  C Kvaal; S A Lachke; T Srikantha; K Daniels; J McCoy; D R Soll
Journal:  Infect Immun       Date:  1999-12       Impact factor: 3.441

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Authors:  J R Naglik; G Newport; T C White; L L Fernandes-Naglik; J S Greenspan; D Greenspan; S P Sweet; S J Challacombe; N Agabian
Journal:  Infect Immun       Date:  1999-05       Impact factor: 3.441

3.  Production, characterization, and epitope mapping of a monoclonal antibody against aspartic proteinase of Candida albicans.

Authors:  B K Na; G T Chung; C Y Song
Journal:  Clin Diagn Lab Immunol       Date:  1999-05

Review 4.  Antifungal agents: chemotherapeutic targets and immunologic strategies.

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Journal:  Antimicrob Agents Chemother       Date:  1996-02       Impact factor: 5.191

Review 5.  Cell wall and secreted proteins of Candida albicans: identification, function, and expression.

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Journal:  Microbiol Mol Biol Rev       Date:  1998-03       Impact factor: 11.056

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Authors:  T C White; L E Andrews; D Maltby; N Agabian
Journal:  J Bacteriol       Date:  1995-05       Impact factor: 3.490

Review 7.  The role of Candida albicans secreted aspartic proteinase in the development of candidoses.

Authors:  L Hoegl; M Ollert; H C Korting
Journal:  J Mol Med (Berl)       Date:  1996-03       Impact factor: 4.599

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Authors:  T C White; S H Miyasaki; N Agabian
Journal:  J Bacteriol       Date:  1993-10       Impact factor: 3.490

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Authors:  B B Magee; B Hube; R J Wright; P J Sullivan; P T Magee
Journal:  Infect Immun       Date:  1993-08       Impact factor: 3.441

10.  Differential expression of secretory aspartyl proteinase genes (SAP1-10) in oral Candida albicans isolates with distinct karyotypes.

Authors:  Arianna Tavanti; Giacomo Pardini; Daniele Campa; Paola Davini; Antonella Lupetti; Sonia Senesi
Journal:  J Clin Microbiol       Date:  2004-10       Impact factor: 5.948

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