| Literature DB >> 1434685 |
M K al-Hindawi1, S H al-Khafaji, M H Abdul-Nabi.
Abstract
The granuloma-tissue formation inhibiting activity of various fractions of an extract of the aerial parts of Withania somnifera were established using subcutaneous cotton-pellet implantation in rats. Antiinflammatory activity was retained in the methanolic fractions of the plant extract and was comparable to that of a 5 mg/kg dose of hydrocortisone sodium succinate. Activity was attributed to the high content of biologically active steroids in the plant, of which withaferin A is known to be a major component.Entities:
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Year: 1992 PMID： 1434685 DOI： 10.1016/0378-8741(92)90069-4
Source DB: PubMed Journal: J Ethnopharmacol ISSN： 0378-8741 Impact factor: 4.360