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Literature DB >> 14329451

ENZYMATIC DEACYLATION OF S35-BENZYLPENICILLIN.

Abstract

Pruess, David L. (University of Wisconsin, Madison), and Marvin J. Johnson. Enzymatic deacylation of S(35)-benzylpenicillin. J. Bacteriol. 90:380-383. 1965.-S(35)-benzylpenicillin, penicilloic acid, and penilloic acid were deacylated by cell suspensions of Escherichia coli and Micrococcus roseus. Both cultures deacylated penicillin most rapidly and penilloic acid least rapidly. The deacylase activity of M. roseus against penicilloic acid was cell-bound, probably requiring a metal ion for activity.

Entities: Chemical Species

Keywords: ACETONE; BUFFERS; CENTRIFUGATION; CHEMISTRY; CHROMATOGRAPHY; CULTURE MEDIA; ESCHERICHIA COLI; EXPERIMENTAL LAB STUDY; FERMENTATION; HYDROGEN-ION CONCENTRATION; METABOLISM; MICROCOCCUS; PENICILLIN G; PHARMACOLOGY; PHENYLACETATES; RADIOMETRY; SULFUR ISOTOPES

Mesh：

Substances：

Year: 1965 PMID： 14329451 PMCID： PMC315654 DOI： 10.1128/jb.90.2.380-383.1965

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

13 in total

1. The distribution of sulfur-containing compounds in penicillin fermentations.

Authors: P L TARDREW; M J JOHNSON
Journal: J Biol Chem Date: 1959-07 Impact factor: 5.157

2. VARIETY OF SUBSTRATES FOR A BACTERIAL BENZYL PENICILLIN-SPLITTING ENZYME.

Authors: W KAUFMANN; K BAUER
Journal: Nature Date: 1964-08-01 Impact factor: 49.962

3. PENICILLIN AMIDASE FROM COLIFORMS: ITS EXTRACTION AND SOME CHARACTERISTICS.

Authors: R J HOLT; G T STEWART
Journal: Nature Date: 1964-02-22 Impact factor: 49.962

4. PRODUCTION OF PENICILLIN ACYLASE.

Authors: A SZENTIRMAI
Journal: Appl Microbiol Date: 1964-05

5. INTERMEDIATES IN INORGANIC SULFATE UTILIZATION BY PENICILLIUM CHRYSOGENUM.

Authors: I H SEGEL; M J JOHNSON
Journal: Arch Biochem Biophys Date: 1963-11 Impact factor: 4.013

6. SPECIFICITY OF PENICILLIN AMIDASES.

Authors: C A CLARIDGE; J R LUTTINGER; J LEIN
Journal: Proc Soc Exp Biol Med Date: 1963 Aug-Sep

7. Comparative study of the binding of synnematin and penicillin by bacterial cells.

Authors: J MOHBERG; M J JOHNSON
Journal: J Bacteriol Date: 1958-10 Impact factor: 3.490

8. Sulfate utilization by penicillin-producing mutants of Penicillium chrysogenum.

Authors: P L TARDREW; M J JOHNSON
Journal: J Bacteriol Date: 1958-10 Impact factor: 3.490

9. Reactions of 6-aminopenicillanic acid with carbohydrates and related substances.

Authors: M O Moss; M Cole
Journal: Biochem J Date: 1964-09 Impact factor: 3.857

10. Distribution and substrate specificity of benzylpenicillin acylase.

Authors: H T HUANG; T A SETO; G M SHULL
Journal: Appl Microbiol Date: 1963-01

10 in total

Review 1. Interaction of penicillin with the bacterial cell: penicillin-binding proteins and penicillin-sensitive enzymes.

Authors: P M Blumberg; J L Strominger
Journal: Bacteriol Rev Date: 1974-09

2. Binding of 14 C-penicillin G to Proteus mirabilis.

Authors: R Schmid; R Plapp
Journal: Arch Mikrobiol Date: 1972

3. Products of acylase and beta-lactamase hydrolysis of some penicillins.

Authors: M Kulhánek; M Tadra
Journal: Folia Microbiol (Praha) Date: 1968 Impact factor: 2.099

Review 4. Penicillinacylase.

Authors: J M Hamilton-Miller
Journal: Bacteriol Rev Date: 1966-12

5. Accessibility of the (14C)benzylpenicillin binding proteins in membranes of sporulating bacilli.

Authors: T E Hamilton; P J Lawrence
Journal: Antimicrob Agents Chemother Date: 1975-07 Impact factor: 5.191

6. Binding of radioactive benzylpenicillin to sporulating Bacillus cultures: chemistry and fluctuations in specific binding capacity.

Authors: P J Lawrence; M Rogolsky; V T Hanh
Journal: J Bacteriol Date: 1971-11 Impact factor: 3.490