Literature DB >> 1425962

Cocaine place preference is blocked by the delta-opioid receptor antagonist, naltrindole.

K Menkens1, E J Bilsky, K D Wild, P S Portoghese, L D Reid, F Porreca.   

Abstract

Naltrindole, a selective delta-opioid receptor antagonist, was evaluated for its potential to block the reinforcing properties of cocaine using a conditioned place pairing paradigm in Lewis rats. Cocaine HCl (15 mg/kg s.c.) produced a strong place preference which was significantly blocked in animals pretreated with naltrindole (3 mg/kg i.p.); naltrindole alone showed no reinforcing or aversive effects. The results suggest a novel approach for the treatment of cocaine abuse in man.

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Year:  1992        PMID： 1425962     DOI： 10.1016/0014-2999(92)90319-y

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  20 in total

1.  5'-halogenated analogs of oxymorphindole.

Authors:  Matthew D Metcalf; Andrew Coop
Journal:  Bioorg Med Chem Lett       Date:  2007-08-23       Impact factor: 2.823

Review 2.  The opioid receptors as targets for drug abuse medication.

Authors:  Florence Noble; Magalie Lenoir; Nicolas Marie
Journal:  Br J Pharmacol       Date:  2015-06-26       Impact factor: 8.739

3.  Delta-opioid receptor-mediated modulation of excitability of individual hippocampal neurons: mechanisms involved.

Authors:  Lucia Moravcikova; Roman Moravcik; Daniela Jezova; Lubica Lacinova; Eliyahu Dremencov
Journal:  Pharmacol Rep       Date:  2020-11-08       Impact factor: 3.024

Review 4.  [The endogenous opioid system and drug addiction].

Authors:  R Maldonado
Journal:  Ann Pharm Fr       Date:  2010-01-21

5.  The mixed-action delta/mu opioid agonist MMP-2200 does not produce conditioned place preference but does maintain drug self-administration in rats, and induces in vitro markers of tolerance and dependence.

Authors:  Glenn W Stevenson; Amy Luginbuhl; Catherine Dunbar; Justin LaVigne; Julio Dutra; Phillip Atherton; Brooke Bell; Katherine Cone; Denise Giuvelis; Robin Polt; John M Streicher; Edward J Bilsky
Journal:  Pharmacol Biochem Behav       Date:  2015-02-28       Impact factor: 3.533

6.  Involvement of delta-opioid receptors in the effects of morphine on locomotor activity and the mesolimbic dopaminergic system in mice.

Authors:  M Narita; T Suzuki; M Funada; M Misawa; H Nagase
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

Review 7.  A neuropeptide-centric view of psychostimulant addiction.

Authors:  B Boutrel
Journal:  Br J Pharmacol       Date:  2008-04-14       Impact factor: 8.739

8.  The selective delta opioid agonist SNC80 enhances amphetamine-mediated efflux of dopamine from rat striatum.

Authors:  Kelly E Bosse; Emily M Jutkiewicz; Margaret E Gnegy; John R Traynor
Journal:  Neuropharmacology       Date:  2008-06-18       Impact factor: 5.250

9.  Influence of naloxone upon motor activity induced by psychomotor stimulant drugs.

Authors:  D N Jones; S G Holtzman
Journal:  Psychopharmacology (Berl)       Date:  1994-03       Impact factor: 4.530

10.  The effects of the kappa agonist U-50,488 on cocaine-induced conditioned and unconditioned behaviors and Fos immunoreactivity.

Authors:  C A Crawford; S A McDougall; C A Bolanos; S Hall; S P Berger
Journal:  Psychopharmacology (Berl)       Date:  1995-08       Impact factor: 4.530
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