Literature DB >> 14175105

GENETICS OF ISONIAZID METABOLISM IN CAUCASIAN, NEGRO, AND JAPANESE POPULATIONS.

A P DUFOUR, R A KNIGHT, H W HARRIS.   

Abstract

Trimodal frequency distributions for isoniazid inactivation were found in Caucasian and Negro populations. The frequency of "rapid" and "slow" alleles in Caucasian and Negro populations was similar and differed from that of a Japanese population.

Entities:  

Keywords:  CAUCASIAN RACE; ISONIAZID; JAPAN; METABOLISM; MONGOLOID RACE; NEGROES

Mesh：

Substances：

Year:  1964        PMID： 14175105

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  14 in total

Review 1.  Ethnic differences in drug disposition and responsiveness.

Authors:  A J Wood; H H Zhou
Journal:  Clin Pharmacokinet       Date:  1991-05       Impact factor: 6.447

2.  High incidence of the slow nitrazepam acetylator phenotype in a Nigerian population.

Authors:  L C Eze
Journal:  Biochem Genet       Date:  1987-04       Impact factor: 1.890

3.  Inactivation of isoniazid by Canadian Eskimos and Indians.

Authors:  C W Jeanes; O Schaefer; L Eidus
Journal:  Can Med Assoc J       Date:  1972-02-19       Impact factor: 8.262

Review 4.  Human polymorphism.

Authors:  J Price
Journal:  J Med Genet       Date:  1967-03       Impact factor: 6.318

5.  The discrimination of phenotypes for rate of disappearance of isonicotinoyl hydrazide from serum.

Authors:  E M Scott; R C Wright; D D Weaver
Journal:  J Clin Invest       Date:  1969-07       Impact factor: 14.808

6.  Partial purification and properties of the isoniazid transacetylase in human liver. Its relationship to the acetylation of p-aminosalicylic acid.

Authors:  J W Jennne
Journal:  J Clin Invest       Date:  1965-12       Impact factor: 14.808

7.  Slow acetylator mutations in the human polymorphic N-acetyltransferase gene in 786 Asians, blacks, Hispanics, and whites: application to metabolic epidemiology.

Authors:  H J Lin; C Y Han; B K Lin; S Hardy
Journal:  Am J Hum Genet       Date:  1993-04       Impact factor: 11.025

8.  Human acetylator polymorphism: estimate of allele frequency in Libya and details of global distribution.

Authors:  A K Karim; M S Elfellah; D A Evans
Journal:  J Med Genet       Date:  1981-10       Impact factor: 6.318

9.  Simultaneous analysis of dapsone and monoacetyldapsone employing high performance liquid chromatography: a rapid method for determination of acetylator phenotype.

Authors:  K Carr; J A Oates; A S Nies; R L Woosley
Journal:  Br J Clin Pharmacol       Date:  1978-11       Impact factor: 4.335

10.  Comparison of CYP1A2 and NAT2 phenotypes between black and white smokers.

Authors:  Joshua E Muscat; Brian Pittman; Wayne Kleinman; Philip Lazarus; Steven D Stellman; John P Richie
Journal:  Biochem Pharmacol       Date:  2008-07-25       Impact factor: 5.858
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