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Literature DB >> 7328611

Human acetylator polymorphism: estimate of allele frequency in Libya and details of global distribution.

Abstract

Acetylator phenotyping by means of a sulphadimidine tests revealed 65% of Libyan Arabs to be slow acetylators. Hence the frequency of the allele controlling slow acetylation (As) is estimated as q = 0.81 +/- 0.05. This estimate is similar to those previously recorded in European and adjacent Middle Eastern populations.

Entities: Chemical Species

Mesh：

Substances：
Acetyltransferases

Year: 1981 PMID： 7328611 PMCID： PMC1048751 DOI： 10.1136/jmg.18.5.325

Source DB: PubMed Journal: J Med Genet ISSN： 0022-2593 Impact factor: 6.318

44 in total

1. [CLINICAL TRIAL OF 3 TYPES OF ORAL TREATMENT OF PULMONARY TUBERCULOSIS. (ISONIAZID+ETHIONAMIDE, ISONIAZID + PAS, ISONIAZID ALONE)].

Authors: M LEHIR; J CHICOU; G HETRICK; A MERCIER; R NEEL; N RIST
Journal: Bull World Health Organ Date: 1964 Impact factor: 9.408

2. GENETICS OF ISONIAZID METABOLISM IN CAUCASIAN, NEGRO, AND JAPANESE POPULATIONS.

Authors: A P DUFOUR; R A KNIGHT; H W HARRIS
Journal: Science Date: 1964-07-24 Impact factor: 47.728

3. [PROBLEMS OF ISONIAZID METABOLISM. HEREDITARY CHARACTER AND VARIABILITY ACCORDING TO RACES].

Authors: S SUNAHARA; M URANO
Journal: Med Thorac Date: 1963

4. FURTHER OBSERVATIONS ON TRIMODALITY OF FREQUENCY DISTRIBUTION CURVE OF BIOLOGICALLY ACTIVE ISONIAZID BLOOD LEVELS AND "CLINE" INFREQUENCIES OF ALLELES CONTROLLING ISONIAZID INACTIVATION.

Authors: S SUNAHARA; M URANO; H T LIN; T J CHEG; A JARUMILINDA
Journal: Acta Tuberc Pneumol Scand Date: 1963

5. Antinuclear factor in rapid and slow acetylator patients treated with isoniazid.

Authors: D A Evans; M F Bullen; J Houston; C A Hopkins; J M Vetters
Journal: J Med Genet Date: 1972-03 Impact factor: 6.318

6. Inactivation of isoniazid (INH) in Swedish tuberculous patients before and during treatment with para-aminosalicylic acid (PAS).

Authors: A Hanngren; O Borgå; F Sjöqvist
Journal: Scand J Respir Dis Date: 1970

7. Comparison of the acetylation of procainamide and sulfadimidine in man.

Authors: K Frislid; M Berg; V Hansteen; P K Lunde
Journal: Eur J Clin Pharmacol Date: 1976-03-22 Impact factor: 2.953

8. The rate of isoniazid inactivation in Finnish diabetic and non-diabetic patients.

Authors: M J Mattila; H Tiitinen
Journal: Ann Med Exp Biol Fenn Date: 1967

9. Acetylation of sulfamethazine in a Nigerian population.

Authors: L C Eze; O Obidoa
Journal: Biochem Genet Date: 1978-12 Impact factor: 1.890

10. Sulphadimidine acetylation test for classification of patients as slow or rapid inactivators of isoniazid.

Authors: K V Rao; D A Mitchison; N G Nair; K Prema; S P Tripathy
Journal: Br Med J Date: 1970-08-29

15 in total

1. Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes.

Authors: Etienne Patin; Luis B Barreiro; Pardis C Sabeti; Frédéric Austerlitz; Francesca Luca; Antti Sajantila; Doron M Behar; Ornella Semino; Anavaj Sakuntabhai; Nicole Guiso; Brigitte Gicquel; Ken McElreavey; Rosalind M Harding; Evelyne Heyer; Lluis Quintana-Murci
Journal: Am J Hum Genet Date: 2006-01-13 Impact factor: 11.025

2. Glucose-6-phosphate dehydrogenase deficiency and sulfadimidin acetylation phenotypes in Egyptian oases.

Authors: L Hussein; G Yamamah; A Saleh
Journal: Biochem Genet Date: 1992-04 Impact factor: 1.890

3. Ecogenetic studies in Atacameño Indians.

Authors: H W Goedde; F Rothhammer; H G Benkmann; P Bogdanski
Journal: Hum Genet Date: 1984 Impact factor: 4.132

4. Slow acetylator mutations in the human polymorphic N-acetyltransferase gene in 786 Asians, blacks, Hispanics, and whites: application to metabolic epidemiology.

Authors: H J Lin; C Y Han; B K Lin; S Hardy
Journal: Am J Hum Genet Date: 1993-04 Impact factor: 11.025