Literature DB >> 14087624

RHEUMATOID FACTOR PROPERTIES OF HYPERIMMUNE RABBIT SERA.

C L CHRISTIAN.   

Abstract

The rheumatoid factor-like substance (RFLS) induced by hyperimmunization of rabbits with bacteria was consistently and exclusively associated with the macroglobulin fraction of the sera studied. The RFLS is separable from the bulk of serum proteins by zone centrifugation, DEAE cellulose chromatography, and gel filtration. Partially purified preparations of the RFLS were studied by immunoelectrophoretic analysis and analytical ultracentrifugation. Certain RFLS sera demonstrated selective reactivity with one or more rabbit isohemagglutinin antibodies. Pepsin treatment of rabbit gamma-globulin removed or greatly diminishes its capacity to react with the RFLS.

Entities:  

Keywords:  AGGLUTINATION; BACILLUS SUBTILIS; ESCHERICHIA COLI; EXPERIMENTAL LAB STUDY; GAMMA GLOBULIN; IMMUNE SERUMS; IMMUNOELECTROPHORESIS; PEPSIN; RABBITS; RHEUMATOID FACTOR; SALMONELLA TYPHIMURIUM

Mesh：

Substances：

Year:  1963        PMID： 14087624      PMCID： PMC2137676          DOI： 10.1084/jem.118.5.827

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  24 in total

1.  Localization of two genetic factors to different areas of gamma-globulin molecules.

Authors:  M HARBOE; C K OSTERLAND; H G KUNKEL
Journal:  Science       Date:  1962-06-15       Impact factor: 47.728

2.  The antibody response to bacteriophage phi-X 174 in newborn premature infants.

Authors:  J W UHR; J DANCIS; E C FRANKLIN; M S FINKELSTEIN; E W LEWIS
Journal:  J Clin Invest       Date:  1962-07       Impact factor: 14.808

3.  Antigenic structure of rabbit gamma globulin.

Authors:  S DUBISKI; A DUBISKA; D SKALBA; A KELUS
Journal:  Immunology       Date:  1961-07       Impact factor: 7.397

4.  Reaction of rheumatoid sera with fragments of papain-digested rabbit gamma globulin.

Authors:  J W GOODMAN
Journal:  Proc Soc Exp Biol Med       Date:  1961-04

5.  STUDIES ON SERUM PROTEINS. I. IDENTIFICATION OF A SINGLE SERUM GLOBULIN BY IMMUNOLOGICAL MEANS. ITS DISTRIBUTION IN THE SERA OF NORMAL INDIVIDUALS AND OF PATIENTS WITH CIRRHOSIS OF THE LIVER AND WITH CHRONIC GLOMERULONEPHRITIS.

Authors:  F E Kendall
Journal:  J Clin Invest       Date:  1937-11       Impact factor: 14.808

6.  SEROLOGIC STUDIES OF PROTEOLYTIC FRAGMENTS OF RABBIT AGGLUTINATING ANTIBODIES.

Authors:  H Fudenberg; W J Mandy; A Nisonoff
Journal:  J Clin Invest       Date:  1962-12       Impact factor: 14.808

7.  The induction of a rheumatoid factor-like substance in rabbits.

Authors:  J L ABRUZZO; C L CHRISTIAN
Journal:  J Exp Med       Date:  1961-11-01       Impact factor: 14.307

8.  Experimental erythroblastosis fetalis in rabbits. I. Characterization of a pair of allelic blood group factors and their specific immune isoantibodies.

Authors:  A KELLNER; E F HEDAL
Journal:  J Exp Med       Date:  1953-01       Impact factor: 14.307

9.  SENSITIZATION TO DENATURED AUTOLOGOUS GAMMA GLOBULIN.

Authors:  R T McCluskey; F Miller; B Benacerraf
Journal:  J Exp Med       Date:  1962-01-01       Impact factor: 14.307

10.  Physical properties of antibody to bovine serum albumin as demonstrated by hemagglutination.

Authors:  A A BENEDICT; R J BROWN; R AYENGAR
Journal:  J Exp Med       Date:  1962-01-01       Impact factor: 14.307
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  17 in total

1.  THE REACTION OF RHEUMATOID FACTOR WITH ANIMAL GAMMA-GLOBULINS: QUANTITATIVE CONSIDERATIONS.

Authors:  V P BUTLER; J H VAUGHAN
Journal:  Immunology       Date:  1965-02       Impact factor: 7.397

2.  Rabbit arthritis induced by cell-free extracts of erysipelothrix.

Authors:  T G White; J L Puls; F K Mirikitani
Journal:  Infect Immun       Date:  1971-06       Impact factor: 3.441

Review 3.  Rheumatoid factor cross idiotypes.

Authors:  V Agnello
Journal:  Springer Semin Immunopathol       Date:  1988

4.  Experimentally produced antibodies to the pepsin site of IgG due to untreated autologous IgG in immune complexes.

Authors:  O J Mellbye; J B Natvig
Journal:  Clin Exp Immunol       Date:  1970-08       Impact factor: 4.330

5.  Elimination of non-specific reaction in latex agglutination test for the detection of hepatitis-associated antigen.

Authors:  E Zalan; C Wilson; N A Labzoffsky
Journal:  Arch Gesamte Virusforsch       Date:  1973

6.  Cell and tissue damage through antigen-antibody complexes.

Authors:  C G Cochrane; F J Dixon
Journal:  Calif Med       Date:  1969-08

7.  Effect of rheumatoid factors and normal human sera on immune complex-Fc gamma R interaction.

Authors:  M A Isturiz; M Giordano; G P Serebrinsky
Journal:  Clin Exp Immunol       Date:  1983-10       Impact factor: 4.330

8.  Rheumatoid factor in the United Kingdom. II. Associations with certain infections.

Authors:  J S Lawrence; H A Valkenburg; A F Tuxford; P J Collard
Journal:  Clin Exp Immunol       Date:  1971-10       Impact factor: 4.330

9.  Experimental induction of rheumatoid factor-like substances in animal trypanosomiasis.

Authors:  F Klein; P Mattern
Journal:  Clin Exp Immunol       Date:  1970-12       Impact factor: 4.330

10.  Anti-gamma globulins and chronic infection: comparative studies of the immune response to various bacteria and gamma globulin preparations.

Authors:  R C Williams; O J Mellbye; G Kronvall
Journal:  Infect Immun       Date:  1972-09       Impact factor: 3.441
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