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Literature DB >> 14074395

PLASMA PROTEIN FORMATION IN VITRO BY TISSUES FROM MICE INFECTED WITH STAPHYLOCOCCI.

Abstract

Isotopic labeling of plasma proteins in vitro by tissues from staphylococcal-infected and control mice was examined, using autoradiography of immunoelectrophoretic patterns. The results indicate that in infected animals there is hyperactivity of liver tissue in producing albumin, alpha- and beta-globulins, and of spleen tissue in producing immune globulins. The observed increase in labeling of some proteins by tissues from infected mice is to a large extent correlated with an increase of these proteins in the serum.

Entities: Disease Species

Keywords: BLOOD PROTEINS; CARBON ISOTOPES; EXPERIMENTAL LAB STUDY; IMMUNOELECTROPHORESIS; LIVER; MICE; RADIOAUTOGRAPHY; SPLEEN; STAPHYLOCOCCAL INFECTIONS; TISSUE CULTURE

Mesh：

Substances：

Year: 1963 PMID： 14074395 PMCID： PMC2137703 DOI： 10.1084/jem.118.2.315

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

10 in total

1. Serum glycoproeins in infectious and inflammatory diseases.

Authors: C L HEISKELL; C M CARPENTER; H E WEIMER; S NAKAGAWA
Journal: Ann N Y Acad Sci Date: 1961-08-31 Impact factor: 5.691

2. A study on correlation between C-reactive protein and certain other acute-phase reactants.

Authors: E W RICE
Journal: Clin Chim Acta Date: 1961-03 Impact factor: 3.786

3. Serum protein fraction response in infection.

Authors: R G GRAHAM; H L DOBSON; E M YOW
Journal: Am J Med Sci Date: 1958-06 Impact factor: 2.378

4. Growth-promoting properties of pyruvate oxal-acetate, and alpha-ketoglutarate for isolated Walker carcinosarcoma 256 cells.

Authors: R E NEUMAN; T A McCOY
Journal: Proc Soc Exp Biol Med Date: 1958-06

5. The clinical significance of the analysis of serum protein distribution by filter paper electrophoresis.

Authors: E L DURRUM; W P JENCKS; E R SMITH
Journal: Am J Med Date: 1956-09 Impact factor: 4.965

6. The growth response of mammalian cells in tissue culture to L-glutamine and L-glutamic acid.

Authors: H EAGLE; V I OYAMA; M LEVY; C L HORTON; R FLEISCHMAN
Journal: J Biol Chem Date: 1956-02 Impact factor: 5.157

7. SITES OF FORMATION OF IMMUNE GLOBULINS AND OF A COMPONENT OF C'(3): I. A NEW TECHNIQUE FOR THE DEMONSTRATION OF THE SYNTHESIS OF INDIVIDUAL SERUM PROTEINS BY TISSUES IN VITRO.

Authors: G M Hochwald; G J Thorbecke; R Asofsky
Journal: J Exp Med Date: 1961-09-30 Impact factor: 14.307

8. The fecal flora of various strains of mice. Its bearing on their susceptibility to endotoxin.

Authors: R W SCHAEDLER; R J DUBOS
Journal: J Exp Med Date: 1962-06-01 Impact factor: 14.307

9. Changes produced in mouse plasma proteins by acute bacterial infections.

Authors: C A WILLIAMS; C T WEMYSS
Journal: J Exp Med Date: 1961-09-01 Impact factor: 14.307

10. SITES OF FORMATION OF IMMUNE GLOBULINS AND OF A COMPONENT OF C'(3): II. PRODUCTION OF IMMUNOELECTROPHORETICALLY IDENTIFIED SERUM PROTEINS BY HUMAN AND MONKEY TISSUES IN VITRO.

Authors: R Asofsky; G J Thorbecke
Journal: J Exp Med Date: 1961-09-30 Impact factor: 14.307

10 in total

19 in total

1. HAPTOGLOBIN SYNTHESIS. I. IN VIVO STUDIES OF THE PRODUCTION OF HAPTOGLOBIN, FIBRINOGEN, AND GAMMA-GLOBULIN BY THE CANINE LIVER.

Authors: C A ALPER; J H PETERS; A G BIRTCH; F H GARDNER
Journal: J Clin Invest Date: 1965-04 Impact factor: 14.808

PLASMA PROTEIN FORMATION IN VITRO BY TISSUES FROM MICE INFECTED WITH STAPHYLOCOCCI.

1. Serum glycoproeins in infectious and inflammatory diseases.

2. A study on correlation between C-reactive protein and certain other acute-phase reactants.

3. Serum protein fraction response in infection.

4. Growth-promoting properties of pyruvate oxal-acetate, and alpha-ketoglutarate for isolated Walker carcinosarcoma 256 cells.

5. The clinical significance of the analysis of serum protein distribution by filter paper electrophoresis.

6. The growth response of mammalian cells in tissue culture to L-glutamine and L-glutamic acid.

7. SITES OF FORMATION OF IMMUNE GLOBULINS AND OF A COMPONENT OF C'(3): I. A NEW TECHNIQUE FOR THE DEMONSTRATION OF THE SYNTHESIS OF INDIVIDUAL SERUM PROTEINS BY TISSUES IN VITRO.

8. The fecal flora of various strains of mice. Its bearing on their susceptibility to endotoxin.

9. Changes produced in mouse plasma proteins by acute bacterial infections.

10. SITES OF FORMATION OF IMMUNE GLOBULINS AND OF A COMPONENT OF C'(3): II. PRODUCTION OF IMMUNOELECTROPHORETICALLY IDENTIFIED SERUM PROTEINS BY HUMAN AND MONKEY TISSUES IN VITRO.

1. HAPTOGLOBIN SYNTHESIS. I. IN VIVO STUDIES OF THE PRODUCTION OF HAPTOGLOBIN, FIBRINOGEN, AND GAMMA-GLOBULIN BY THE CANINE LIVER.

2. SYNTHESIS OF SERUM PROTEINS BY A CELL-FREE SYSTEM FROM RAT LIVER.

3. EFFECT OF BACTERIAL INFECTION ON THE SYNTHESIS OF SERUM PROTEINS BY A MOUSE LIVER CELL-FREE SYSTEM.

4. The formation of immunoglobulins by human tissues in vitro. I. The methods and their specificity.

5. Beta-1C and immune globulin formation in vitro by tissues from germ-free and conventional rodents of various ages.

6. Production of alpha-1-globulins by the perfused rat liver.

7. Formation of C'-6 by rabbit liver tissue in vitro.

8. Auto-reactivity to haemoglobin in the sera of cattle and sheep infected with haemolytic bacteria.

9. Immunohistochemical localization of human alpha 2Macroglobulin in connective tissue.

10. Tissue amino acid flux after exposure of rats to Diplococcus pneumoniae.