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Literature DB >> 19867196

SITES OF FORMATION OF IMMUNE GLOBULINS AND OF A COMPONENT OF C'(3): II. PRODUCTION OF IMMUNOELECTROPHORETICALLY IDENTIFIED SERUM PROTEINS BY HUMAN AND MONKEY TISSUES IN VITRO.

Abstract

Human, and monkey tissues were cultured in the presence of labeled amino acid. The culture fluids were then examined for labeled serum proteins by means of autoradiography of immunoelectrophoretic patterns prepared from mixtures of the fluids and carrier sera. Gamma globulin, beta(2A)-globulin, beta(2M)globulin, and beta(1C)-globulin were found to be formed in human lymph node, bone marrow, and ileum. Gamma globulin, beta(2M)-globulin, and beta(1C)-globulin were found to be formed in monkey spleen, lymph node, and bone marrow. Formation of several other serum proteins was observed in the monkey liver.

Entities: Disease Species

Year: 1961 PMID： 19867196 PMCID： PMC2180363 DOI： 10.1084/jem.114.4.471

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

19 in total

1. Possible sites of macroglobulin synthesis: a study made with fluorescent antibody.

Authors: C C CURTAIN; J F O'DEA
Journal: Australas Ann Med Date: 1959-05

2. In vitro formation of 7S and 19S gamma-globulins by tissues from normal subjects and patients with rheumatoid arthritis.

Authors: H I LEVENE; E C FRANKLIN; G J THORBECKE
Journal: J Immunol Date: 1961-04 Impact factor: 5.422

3. Two transplantable mouse hepatomas associated with an increase of metal-combining beta-globulin (transferrin) in serum.

Authors: J CLAUSEN; R RASK-NIELSEN; H E CHRISTENSEN; T MUNKNER
Journal: Cancer Res Date: 1960-02 Impact factor: 12.701

4. The synthesis of antibodies and proteins.

Authors: H E SCHULTZE
Journal: Clin Chim Acta Date: 1959-09 Impact factor: 3.786

5. Immunochemical studies on protein pathology. The immunoglobulin concept.

Authors: J F HEREMANS
Journal: Clin Chim Acta Date: 1959-09 Impact factor: 3.786

6. Antibody and gamma globulin formation in vitro in hemopoietic organs.

Authors: G J THORBECKE; F J KEUNING
Journal: J Infect Dis Date: 1956 Mar-Apr Impact factor: 5.226

7. Relation of plasma cell growth to abnormal serum protein components and Bence Jones proteinuria in multiple myeloma.

Authors: R W RUNDLES; M L DILLON; E S DILLON; G R COOPER
Journal: J Clin Invest Date: 1950-06 Impact factor: 14.808

8. CELLULAR ORIGIN OF RHEUMATOID FACTOR.

Authors: R C Mellors; R Heimer; J Corcos; L Korngold
Journal: J Exp Med Date: 1959-11-30 Impact factor: 14.307

9. Gamma globulin and antibody formation in vitro. I. Gamma globulin formation in tissues from immature and normal adult rabbits.

Authors: G J THORBECKE
Journal: J Exp Med Date: 1960-08-01 Impact factor: 14.307

10. Isolation and characterization of two beta1-glycoproteins of human serum.

Authors: H J MULLER-EBERHARD; U NILSSON; T ARONSSON
Journal: J Exp Med Date: 1960-02-01 Impact factor: 14.307

11 in total

1. Cultivation of lymphatic cells in protein-free medium and chemical study of the products.

Authors: M POSPISIL; F FRANEK
Journal: Folia Microbiol (Praha) Date: 1963-01 Impact factor: 2.099

2. [Immunopathology in Hodgkin's disease].

Authors: P G Scheurlen
Journal: Z Krebsforsch Klin Onkol Cancer Res Clin Oncol Date: 1972

3. [Chimerism of type O-B in two currently discovered cases with difference in the Lewis-groups and the antigen activity of H and P1].

Authors: A Kaeser; H J Nennstiel
Journal: Blut Date: 1971-05

Review 4. The bone marrow: the major source of serum immunoglobulins, but still a neglected site of antibody formation.

Authors: R Benner; W Hijmans; J J Haaijman
Journal: Clin Exp Immunol Date: 1981-10 Impact factor: 4.330

5. Modifications of serum glycoproteins the days following a prolonged physical exercise and the influence of physical training.

Authors: H Liesen; B Dufaux; W Hollmann
Journal: Eur J Appl Physiol Occup Physiol Date: 1977-12-22

6. [Quantitative behavior of IgG, IgA and IgM as well as transferrin, ceruloplasmin, alpha-1 antitrypsin and beta-1 A-globulin in normal persons over a period of 5 months].

Authors: W Mondorf; M Kollman
Journal: Klin Wochenschr Date: 1969-10-01

7. SITES OF FORMATION OF IMMUNE GLOBULINS AND OF A COMPONENT OF C'(3): I. A NEW TECHNIQUE FOR THE DEMONSTRATION OF THE SYNTHESIS OF INDIVIDUAL SERUM PROTEINS BY TISSUES IN VITRO.

Authors: G M Hochwald; G J Thorbecke; R Asofsky
Journal: J Exp Med Date: 1961-09-30 Impact factor: 14.307