Literature DB >> 13905041

Studies on fluorinated pyrimidines. XIII. Inhibition of thymidylate synthetase.

K U HARTMANN, C HEIDELBERGER.   

Abstract

Entities:  

Keywords:  ENZYMES/antagonists; NUCLEOSIDES AND NUCLEOTIDES/chemistry; PYRIMIDINES/chemistry

Mesh：

Substances：

Year:  1961        PMID： 13905041

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


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  70 in total

1.  STUDIES ON NORMAL AND LEUKEMIC LEUKOCYTES. VI. THYMIDYLATE SYNTHETASE AND DEOXYCYTIDYLATE DEAMINASE.

Authors:  R SILBER; B W GABRIO; F M HUENNEKENS
Journal:  J Clin Invest       Date:  1963-12       Impact factor: 14.808

2.  THE EFFECT OF 5-FLUORODEOXYURIDINE ON GENETIC REPLICATION AND MITOTIC CROSSING OVER IN SYNCHRONIZED CULTURES OF USTILAGO MAYDIS.

Authors:  R E ESPOSITO; R HOLLIDAY
Journal:  Genetics       Date:  1964-11       Impact factor: 4.562

3.  The teratogenic effects of 5-fluoro-2-desoxyuridine (F.U.D.R.) on the Wistar rat fetus with particular reference to cleft palate.

Authors:  M W Ferguson
Journal:  J Anat       Date:  1978-05       Impact factor: 2.610

4.  DNA synthesis as a therapeutic target: the first 65 years.

Authors:  Christopher K Mathews
Journal:  FASEB J       Date:  2012-06       Impact factor: 5.191

5.  A method for testing the specificity of inhibitors of deoxyribonucleic Acid synthesis in growth studies.

Authors:  A H Haber; O J Schwarz
Journal:  Plant Physiol       Date:  1972-03       Impact factor: 8.340

6.  CELL DIVISION AND THE DIFFERENTIATION OF WOUND-VESSEL MEMBERS IN CULTURED STEM SEGMENTS OF Coleus.

Authors:  D E Fosket
Journal:  Proc Natl Acad Sci U S A       Date:  1968-04       Impact factor: 11.205

7.  Trifluorothymidine exhibits potent antitumor activity via the induction of DNA double-strand breaks.

Authors:  Norihiko Suzuki; Fumio Nakagawa; Mamoru Nukatsuka; Masakazu Fukushima
Journal:  Exp Ther Med       Date:  2011-03-21       Impact factor: 2.447

8.  5,10-Methylene-5,6,7,8-tetrahydrofolate conformational transitions upon binding to thymidylate synthase: molecular mechanics and continuum solvent studies.

Authors:  Adam Jarmuła; Piotr Cieplak; William R Montfort
Journal:  J Comput Aided Mol Des       Date:  2005-02       Impact factor: 3.686

9.  Usefulness of alternate-day administration of S-1 and leucovorin in a xenograft mouse model of colorectal cancer: a shorter drug-free interval leads to more efficient antitumor effects.

Authors:  Toshihiro Komura; Koh Miura; Tetsuhiko Shirasaka; Shinobu Ohnuma; Miki Shimada; Taiki Kajiwara; Fumiyoshi Fujishima; Alex Philchenkov; Kei Nakagawa; Katsuyoshi Kudoh; Sho Haneda; Masahide Toshima; Atsushi Kohyama; Hiroaki Musha; Takeshi Naitoh; Chikashi Shibata; Michiaki Unno
Journal:  Int J Clin Oncol       Date:  2014-05-08       Impact factor: 3.402

10.  Phosphorolysis of 5-fluoro-2'-deoxyuridine in Escherichia coli and its inhibition by nucleosides.

Authors:  E Yagil; A Rosner
Journal:  J Bacteriol       Date:  1971-11       Impact factor: 3.490
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