Literature DB >> 4256858

Phosphorolysis of 5-fluoro-2'-deoxyuridine in Escherichia coli and its inhibition by nucleosides.

E Yagil, A Rosner.   

Abstract

The effect of ribonucleosides and deoxyribonucleosides on the phosphorolysis of 5-fluoro-2'-deoxyuridine (FUdR) was examined in cells of Escherichia coli. All nucleosides tested except guanosine and deoxyguanosine inhibited phosphorolysis. By using genetically marked strains it was found that in vivo FUdR is a specific substrate of thymidine phosphorylase.

Entities:  

Mesh：

Substances：

Year:  1971        PMID： 4256858      PMCID： PMC247137          DOI： 10.1128/jb.108.2.760-764.1971

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  22 in total

1.  A deoxythymidine kinase-deficient mutant of Escherichia coli. I. Isolation and some properties.

Authors:  S Hiraga; K Igarashi; T Yura
Journal:  Biochim Biophys Acta       Date:  1967-08-22

2.  Specificity and efficiency of thymidine incorporation in Escherichia coli lacking thymidine phosphorylase.

Authors:  W L Fangman
Journal:  J Bacteriol       Date:  1969-09       Impact factor: 3.490

Review 3.  Current linkage map of Escherichia coli.

Authors:  A L Taylor
Journal:  Bacteriol Rev       Date:  1970-06

4.  The effect of nucleosides on the phosphorolysis of thymidine by normal and phage-infected cells of E. coli.

Authors:  J Doskocil; V Paces
Journal:  Biochem Biophys Res Commun       Date:  1968-01-25       Impact factor: 3.575

5.  Ribosyl and deoxyribosyl transfer by bacterial enzyme systems.

Authors:  A Imada; S Igarasi
Journal:  J Bacteriol       Date:  1967-11       Impact factor: 3.490

6.  Thymidine breakdown and thymine uptake in different mutants of Escherichia coli.

Authors:  A Munch-Petersen
Journal:  Biochim Biophys Acta       Date:  1967-06-20

7.  On the catabolism of deoxyribonucleosides in cells and cell extracts of Escherichia coli.

Authors:  A Munch-Petersen
Journal:  Eur J Biochem       Date:  1968-11

8.  Structural requirements for the inhibition of uridine-deoxyuridine phosphorylase by thymine nucleosides containing an unnatural carbohydrate moiety.

Authors:  G Etzold; B Preussel; P Langen
Journal:  Mol Pharmacol       Date:  1968-01       Impact factor: 4.436

Review 9.  Cancer chemotherapy with purine and pyrimidine analogues.

Authors:  C Heidelberger
Journal:  Annu Rev Pharmacol       Date:  1967       Impact factor: 13.820

10.  Effect of adenosine and deoxyadenosine on the incorporation and breakdown of thymidine in Escherichia coli K-12.

Authors:  E Yagil; A Rosner
Journal:  J Bacteriol       Date:  1970-08       Impact factor: 3.490
View more
  11 in total

1.  Uptake of adenosine 5'-monophosphate by Escherichia coli.

Authors:  E Yagil; I R Beacham
Journal:  J Bacteriol       Date:  1975-02       Impact factor: 3.490

2.  SP62, a viable mutant of bacteriophage T4D defective in regulation of phage enzyme synthesis.

Authors:  J S Wiberg; S Mendelsohn; V Warner; K Hercules; C Aldrich; J L Munro
Journal:  J Virol       Date:  1973-10       Impact factor: 5.103

3.  R factor elimination by inhibitors of thymidylate synthetase (fluorodeoxyuridine and showdomycin) and the occurrence of single strand breaks in plasmid DNA.

Authors:  R J Pinney; K Bremer; J T Smith
Journal:  Mol Gen Genet       Date:  1974

4.  Deoxythymidine nucleotide metabolism in Bacillus subtilis W23 infected with bacteriophage SP1Oc: preliminary evidence that dTMP in SP10c DNA is synthesized by a novel, bacteriophage-specific mechanism.

Authors:  O Markewych; E Casella; M Dosmar; H Witmer
Journal:  J Virol       Date:  1979-01       Impact factor: 5.103

5.  Degree of participation of exogenous thymidine in the overall deoxyribonucleic acid synthesis in Escherichia coli.

Authors:  D Rosenbaum-Oliver; S Zamenhof
Journal:  J Bacteriol       Date:  1972-05       Impact factor: 3.490

6.  Effect of the folic acid analogue, trimethoprim, on growth, macromolecular synthesis, and incorporation of exogenous thymine in Escherichia coli.

Authors:  B A Dale; G R Greenberg
Journal:  J Bacteriol       Date:  1972-06       Impact factor: 3.490

7.  Production and expression of dTMP-enriched DNA of bacteriophage SP15.

Authors:  E Casella; O Markewych; M Dosmar; H Witmer
Journal:  J Virol       Date:  1978-12       Impact factor: 5.103

8.  Biosynthesis of 5-(4'5'-dihydroxypentyl) uracil as a nucleoside triphosphate in bacteriophage SP15-infected Bacillus subtilis.

Authors:  M S Walker; M Mandel
Journal:  J Virol       Date:  1978-02       Impact factor: 5.103

9.  Trimethoprim action and its analogy with thymine starvation.

Authors:  S G Amyes; J T Smith
Journal:  Antimicrob Agents Chemother       Date:  1974-02       Impact factor: 5.191

10.  Pyrimidine metabolism of Bdellovibrio bacteriovorus grown intraperiplasmically and axenically.

Authors:  R A Rosson; S C Rittenberg
Journal:  J Bacteriol       Date:  1981-04       Impact factor: 3.490
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.