Literature DB >> 22653564

DNA synthesis as a therapeutic target: the first 65 years.

Christopher K Mathews1.   

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Year:  2012        PMID： 22653564      PMCID： PMC4052436          DOI： 10.1096/fj.12-0602ufm

Source DB:  PubMed          Journal:  FASEB J        ISSN： 0892-6638            Impact factor:   5.191


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  28 in total

1.  Direct spectrophotometric evidence for the oxidation of tetrahydrofolate during the enzymatic synthesis of thymidylate.

Authors:  A J WAHBA; M FRIEDKIN
Journal:  J Biol Chem       Date:  1961-03       Impact factor: 5.157

2.  THE MODE OF ACTION OF 5-FLUOROURACIL AND ITS DERIVATIVES.

Authors:  S S Cohen; J G Flaks; H D Barner; M R Loeb; J Lichtenstein
Journal:  Proc Natl Acad Sci U S A       Date:  1958-10-15       Impact factor: 11.205

Review 3.  Ribonucleotide reductases.

Authors:  J Stubbe
Journal:  Adv Enzymol Relat Areas Mol Biol       Date:  1990

4.  Effect of the thymidylate synthase inhibitors on dUTP and TTP pool levels and the activities of DNA repair glycosylases on uracil and 5-fluorouracil in DNA.

Authors:  Breeana C Grogan; Jared B Parker; Amy F Guminski; James T Stivers
Journal:  Biochemistry       Date:  2011-01-11       Impact factor: 3.162

Review 5.  Chemical carcinogenesis, chemotherapy: cancer's continuing core challenges--G. H. A. Clowes Memorial Lecture.

Authors:  C Heidelberger
Journal:  Cancer Res       Date:  1970-06       Impact factor: 12.701

6.  Overproduction of the free radical of ribonucleotide reductase in hydroxyurea-resistant mouse fibroblast 3T6 cells.

Authors:  L Akerblom; A Ehrenberg; A Gräslund; H Lankinen; P Reichard; L Thelander
Journal:  Proc Natl Acad Sci U S A       Date:  1981-04       Impact factor: 11.205

Review 7.  Gene amplification in cultured animal cells.

Authors:  R T Schimke
Journal:  Cell       Date:  1984-07       Impact factor: 41.582

Review 8.  Chemotherapy and comparative biochemistry: G. H. A. Clowes memorial lecture.

Authors:  G H Hitchings
Journal:  Cancer Res       Date:  1969-11       Impact factor: 12.701

9.  Functional consequences of the arabinosylcytosine structural lesion in DNA.

Authors:  T Mikita; G P Beardsley
Journal:  Biochemistry       Date:  1988-06-28       Impact factor: 3.162

10.  Effects of arabinosylcytosine-substituted DNA on DNA/RNA hybrid stability and transcription by T7 RNA polymerase.

Authors:  T Mikita; G P Beardsley
Journal:  Biochemistry       Date:  1994-08-09       Impact factor: 3.162
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  4 in total

1.  Methotrexate promotes glucose uptake and lipid oxidation in skeletal muscle via AMPK activation.

Authors:  Sergej Pirkmajer; Sameer S Kulkarni; Robby Z Tom; Fiona A Ross; Simon A Hawley; D Grahame Hardie; Juleen R Zierath; Alexander V Chibalin
Journal:  Diabetes       Date:  2014-10-22       Impact factor: 9.461

2.  Impact of the 2'- and 3'-Sugar Hydroxyl Moieties on Gas-Phase Nucleoside Structure.

Authors:  L A Hamlow; Zachary J Devereaux; H A Roy; N A Cunningham; G Berden; J Oomens; M T Rodgers
Journal:  J Am Soc Mass Spectrom       Date:  2019-03-08       Impact factor: 3.109

3.  Effects of thymidylate synthase polymorphisms on toxicities associated with high-dose methotrexate in childhood acute lymphoblastic leukemia.

Authors:  Abrar Al-Sheikh; Al-Motassem Yousef; Daniah Alshamaseen; Rand Farhad
Journal:  Cancer Chemother Pharmacol       Date:  2020-11-10       Impact factor: 3.333

4.  CHCHD4 regulates tumour proliferation and EMT-related phenotypes, through respiratory chain-mediated metabolism.

Authors:  Luke W Thomas; Cinzia Esposito; Jenna M Stephen; Ana S H Costa; Christian Frezza; Thomas S Blacker; Gyorgy Szabadkai; Margaret Ashcroft
Journal:  Cancer Metab       Date:  2019-07-16
  4 in total

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