| Literature DB >> 1377011 |
T Ried1, C Lengauer, T Cremer, J Wiegant, A K Raap, M van der Ploeg, P Groitl, M Lipp.
Abstract
Triple fluorescence in situ hybridization with a plasmid DNA library from sorted human chromosomes 8 in combination with bacteriophage clones flanking the breakpoint in 8q24 of the Burkitt lymphoma cell line J1 was used for the specific delineation of this breakpoint in individual tumor cells. With this approach, tumor-specific breakpoints in translocation chromosomes can be detected at all stages of the cell cycle with high specificity.Entities:
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Year: 1992 PMID: 1377011 DOI: 10.1002/gcc.2870040109
Source DB: PubMed Journal: Genes Chromosomes Cancer ISSN: 1045-2257 Impact factor: 5.006