| Literature DB >> 13766661 |
Abstract
The production of a fraction of the rifomycin complex (rifomycin B) by Streptomyces mediterranei has been described. Both qualitative and quantitative aspects of the fermentation are determined by suitable agitation-aeration parameters. In addition to conventional nutrient ingredients, the presence of some of the barbituric acid derivatives was found to be essential for rifomycin B production. An attempt was made to explain the mode of action of these compounds.Entities:
Keywords: ANTIBIOTICS/metabolism; STREPTOMYCES/metabolism
Mesh:
Substances:
Year: 1961 PMID: 13766661 PMCID: PMC1057734 DOI: 10.1128/am.9.4.325-334.1961
Source DB: PubMed Journal: Appl Microbiol ISSN: 0003-6919