Literature DB >> 13678938

Significant gender-related differences in radiofrequency catheter ablation therapy.

Nikolaos Dagres1, Jonathan R Clague, Günter Breithardt, Martin Borggrefe.   

Abstract

OBJECTIVES: We investigated possible differences between male and female patients regarding ablation therapy.
BACKGROUND: Gender-related differences might have a major impact on different aspects of radiofrequency ablation therapy. Data on this topic are very limited, focusing almost exclusively on success and recurrence rates.
METHODS: The study population consisted of 894 consecutive patients who underwent catheter ablation of accessory pathways (n = 519) and/or atrioventricular nodal re-entrant tachycardia (AVNRT) (n = 379). There were 418 (46.8%) male and 476 (53.2%) female patients.
RESULTS: Female patients were referred for ablation later than male patients (185 +/- 143 vs. 157 +/- 144 months after onset of symptoms, p < 0.001) and after having been given more antiarrhythmic drugs (1.6 +/- 1.2 vs. 1.3 +/- 1.1, p < 0.001). Women were more symptomatic, with a higher number of patients having >1 tachycardia episode per month (80.3% vs. 70.3% in men, p < 0.001). Fluoroscopy time, radiofrequency applications, and procedure duration were similar in male and female patients undergoing accessory pathway ablation as well as in male and female patients undergoing AVNRT ablation. No difference was seen in success, complication, and recurrence rates between men and women.
CONCLUSIONS: Physicians and/or patients tend toward a more conservative approach in female patients. Women are referred for ablation later than are men, after a longer duration of symptoms, and after having been given more antiarrhythmic drugs. However, potential concerns on behalf of physicians or female patients do not seem to be justified: ablation procedures in women had equally high success, low complication, and low recurrence rates as those procedures in male patients.

Entities:  

Mesh:

Year:  2003        PMID: 13678938     DOI: 10.1016/s0735-1097(03)00925-2

Source DB:  PubMed          Journal:  J Am Coll Cardiol        ISSN: 0735-1097            Impact factor:   24.094


  17 in total

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Review 3.  Arrhythmias in women.

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Review 4.  Gender Differences in Arrhythmias: Focused on Atrial Fibrillation.

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Journal:  J Cardiovasc Transl Res       Date:  2019-10-21       Impact factor: 4.132

Review 5.  Catheter Ablation of Atrial Fibrillation in Females.

Authors:  Daniela Dugo; Stefano Bordignon; Laura Perrotta; Alexander Fürnkranz; K R Julian Chun; Boris Schmidt
Journal:  J Atr Fibrillation       Date:  2013-06-30

6.  Influence of age, sex, and atrial fibrillation recurrence on quality of life outcomes in a population of patients with new-onset atrial fibrillation: the Fibrillation Registry Assessing Costs, Therapies, Adverse events and Lifestyle (FRACTAL) study.

Authors:  Matthew R Reynolds; Tara Lavelle; Vidal Essebag; David J Cohen; Peter Zimetbaum
Journal:  Am Heart J       Date:  2006-12       Impact factor: 4.749

7.  Development and initial psychometric evaluation of the Patient Perspective of Arrhythmia Questionnaire.

Authors:  Kathryn A Wood; Anita L Stewart; Barbara J Drew; Melvin M Scheinman; Erika S Frolicher
Journal:  Res Nurs Health       Date:  2009-10       Impact factor: 2.228

8.  Gender differences in onset of symptoms in AV nodal re-entrant and accessory pathway-mediated re-entrant tachycardia.

Authors:  T Deneke; P Müller; T Lawo; B Lemke; M Horlitz; B Calcum; L-I Bösche; A Mügge; P H Grewe
Journal:  Herzschrittmacherther Elektrophysiol       Date:  2009-04-18

9.  Influence of Age and Gender on Complications of Catheter Ablation for Atrial Fibrillation.

Authors:  Giuseppe Stabile; Emanuele Bertaglia; Carlo Pappone; Sakis Themistoclakis; Claudio Tondo; Alessandro Zorzi; Matteo Anselmino
Journal:  J Atr Fibrillation       Date:  2015-04-30

10.  Outcomes in Women Undergoing Electrophysiological Procedures.

Authors:  Pasquale Santangeli; Luigi Di Biase; Eloisa Basile; Amin Al-Ahmad; Andrea Natale
Journal:  Arrhythm Electrophysiol Rev       Date:  2013-04
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