Literature DB >> 1363504

Immunization with fimbrial protein and peptide protects against Porphyromonas gingivalis-induced periodontal tissue destruction.

R T Evans1, B Klausen, R J Genco.   

Abstract

In these studies we have attempted to show that cell surface structures are critical antigens for protection against P. gingivalis-induced periodontal destruction. Fimbrillin, and in particular a synthetic 20-amino-acid fimbrillin peptide, exerts a protective effect in gnotobiotic rats, thus identifying them as potentially useful in the development of a vaccine.

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Year:  1992        PMID: 1363504     DOI: 10.1007/978-1-4615-3410-5_27

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  10 in total

Review 1.  Bacterially induced bone destruction: mechanisms and misconceptions.

Authors:  S P Nair; S Meghji; M Wilson; K Reddi; P White; B Henderson
Journal:  Infect Immun       Date:  1996-07       Impact factor: 3.441

2.  Increased susceptibility of RAG-2 SCID mice to dissemination of endodontic infections.

Authors:  R Teles; C Y Wang; P Stashenko
Journal:  Infect Immun       Date:  1997-09       Impact factor: 3.441

3.  Expression of functional Porphyromonas gingivalis fimbrillin polypeptide domains on the surface of Streptococcus gordonii.

Authors:  A Sharma; H Nagata; N Hamada; H T Sojar; D E Hruby; H K Kuramitsu; R J Genco
Journal:  Appl Environ Microbiol       Date:  1996-11       Impact factor: 4.792

4.  Porphyromonas gingivalis fimbria-stimulated bone resorption in vitro is inhibited by a tyrosine kinase inhibitor.

Authors:  S Hanazawa; Y Kawata; Y Murakami; K Naganuma; S Amano; Y Miyata; S Kitano
Journal:  Infect Immun       Date:  1995-06       Impact factor: 3.441

5.  Oral immunization with recombinant Streptococcus gordonii expressing porphyromonas gingivalis FimA domains.

Authors:  A Sharma; K Honma; R T Evans; D E Hruby; R J Genco
Journal:  Infect Immun       Date:  2001-05       Impact factor: 3.441

6.  Porphyromonas gingivalis fimbria-stimulated bone resorption is inhibited through binding of the fimbriae to fibronectin.

Authors:  Y Kawata; H Iwasaka; S Kitano; S Hanazawa
Journal:  Infect Immun       Date:  1997-02       Impact factor: 3.441

Review 7.  Oral microbial ecology and the role of salivary immunoglobulin A.

Authors:  H Marcotte; M C Lavoie
Journal:  Microbiol Mol Biol Rev       Date:  1998-03       Impact factor: 11.056

8.  Production of Monoclonal Antibodies Specific to FimA of Porphyromonas gingivalis and Their Inhibitory Activity on Bacterial Binding.

Authors:  Eun-Mi Koh; Ju Kim; Jin-Yong Lee; Tae-Geum Kim
Journal:  Immune Netw       Date:  2009-10-30       Impact factor: 6.303

9.  Porphyromonas gingivalis fimbriae stimulate bone resorption in vitro.

Authors:  Y Kawata; S Hanazawa; S Amano; Y Murakami; T Matsumoto; K Nishida; S Kitano
Journal:  Infect Immun       Date:  1994-07       Impact factor: 3.441

10.  Porphyromonas gingivalis-specific immunoglobulin G prevents P. gingivalis-elicited oral bone loss in a murine model.

Authors:  Frank C Gibson; Dario A Gonzalez; Jodie Wong; Caroline Attardo Genco
Journal:  Infect Immun       Date:  2004-04       Impact factor: 3.441

  10 in total

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