Literature DB >> 135687

Micromethods for induction and assay of mouse mixed lymphocyte reactions and cytotoxicity.

E Simpson, R Gordon, M Taylor, J Mertin, P Chandler.   

Abstract

A new method in which induction of mixed lymphocyte responses and cytotoxicity can be performed under identical conditions is described. This enables the investigation of the relationship between MLR and cytotoxicity. A micro method for the 51Cr release assay for cytotoxicity is described using both mitogen-induced blasts and tumors as target cells. Under the conditions used data obtained is suitable for linear regression analysis, enabling quantitative comparisons to be made.

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Year:  1976        PMID： 135687     DOI： 10.1002/eji.1830050705

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN： 0014-2980            Impact factor:   5.532


  24 in total

1.  The differentiation of cytotoxic T lymphocytes in vitro: an ultrastructural study.

Authors:  A Matter; E Simpson
Journal:  Cell Tissue Res       Date:  1976-02-27       Impact factor: 5.249

2.  Interferon enhances T cell mediated cytotoxicity of H-2 compatible target cells infected with UV-inactivated herpes simplex virus.

Authors:  K K Sethi; H Brandis
Journal:  Arch Virol       Date:  1978       Impact factor: 2.574

3.  Tumour-induced immunity to H-Y-disparate skin grafts without concomitant priming of CTL.

Authors:  L L Johnson; D L Hines
Journal:  Immunology       Date:  1990-01       Impact factor: 7.397

4.  Immunoregulatory responses in experimental disseminated histoplasmosis: depression of T-cell-dependent and T-effectory responses by activation of splenic suppressor cells.

Authors:  R P Artz; W E Bullock
Journal:  Infect Immun       Date:  1979-03       Impact factor: 3.441

5.  H-2-associated differences in replicated strains of mice divergently selected for body weight.

Authors:  E Simpson; G Bulfield; M Brenan; W Fitzpatrick; C Heterington; A Blann
Journal:  Immunogenetics       Date:  1982-01       Impact factor: 2.846

Review 6.  HLA restriction of human cytotoxic T cells.

Authors:  A J McMichael
Journal:  Springer Semin Immunopathol       Date:  1980-05

7.  Autologous lymphoid cells exposed to recombinant interleukin-2 in vitro in the absence of antigen can induce the rejection of long-term tolerated skin allografts.

Authors:  B Loveland; R Hunt; M Malkovský
Journal:  Immunology       Date:  1986-09       Impact factor: 7.397

8.  Immune responsiveness following intratracheal inoculation with Histoplasma capsulatum yeast cells.

Authors:  D A Nickerson; P Fairclough
Journal:  Clin Exp Immunol       Date:  1984-05       Impact factor: 4.330

9.  Enhancement of specific antitumor immunity in mice fed a diet enriched in vitamin A acetate.

Authors:  M Malkovský; C Doré; R Hunt; L Palmer; P Chandler; P B Medawar
Journal:  Proc Natl Acad Sci U S A       Date:  1983-10       Impact factor: 11.205

10.  Fine-specificity of the immune response to oxazolones. IV. Furyloxazolone-specific cytolytic T lymphocytes (unlike antibodies) are not heteroclitic.

Authors:  A Matoso-Ferreira
Journal:  Immunology       Date:  1984-11       Impact factor: 7.397
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