Literature DB >> 1350464

Relation between 25-hydroxyvitamin D3, apolipoprotein A-I, and high density lipoprotein cholesterol.

J Auwerx1, R Bouillon, H Kesteloot.   

Abstract

In a survey of cardiovascular risk factors in 185 men and 173 women of a Belgian population group, an independent and highly significant positive correlation was found between the serum concentrations of 25-hydroxyvitamin D3 and apolipoprotein A-I (p less than 0.001 in both sexes). 25-Hydroxyvitamin D3 also showed a positive correlation with high density lipoprotein cholesterol levels (p less than 0.05 in men and p less than 0.005 in women). This relation was independent of a possible effect of 25-hydroxyvitamin D3 on serum calcium. Taking the biological variation of 25-hydroxyvitamin D3 levels (+/- 2 SD = 25 ng/ml) into account, these findings could explain variations in the levels of apolipoprotein A-I of 15 mg/100 ml and of high density lipoprotein cholesterol of 4 mg/100 ml.

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Year:  1992        PMID： 1350464     DOI： 10.1161/01.atv.12.6.671

Source DB:  PubMed          Journal:  Arterioscler Thromb        ISSN： 1049-8834


  32 in total

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Review 10.  Theoretical basis of a beneficial role for vitamin D in viral hepatitis.

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