Literature DB >> 1349563

Anonymous markers located on chromosome 6 in the HLA-A class I region: allelic distribution in genetic haemochromatosis.

J Boretto1, A M Jouanolle, J Yaouanq, A el Kahloun, V Mauvieux, M Blayau, M Perichon, A Le Treut, J Clayton, N Borot.   

Abstract

Two yeast artificial chromosomes of the HLA class I region were subcloned. Four of the subclones studied displayed restriction polymorphisms that corresponded to six bi-allelic series. Allelic distribution of the anonymous markers was then studied by comparing a control population with a group of patients with familial haemochromatosis. Only one marker presents an unequivocal association with the haemochromatosis gene and is 100 kb centromeric to HLA-A. This association however is not as strong as with HLA-A3. The results suggest two possible locations for the haemochromatosis gene: less than 100 kb centromeric to the HLA-A locus, or on the telomeric side.

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Year:  1992        PMID： 1349563     DOI： 10.1007/bf00207038

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  22 in total

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Journal:  Nouv Presse Med       Date:  1975-05-10

2.  Molecular analysis of the human MHC class I region using yeast artificial chromosome clones.

Authors:  G Chimini; J Boretto; D Marguet; F Lanau; G Lauquin; P Pontarotti
Journal:  Immunogenetics       Date:  1990       Impact factor: 2.846

3.  Prevalence of hemochromatosis among 11,065 presumably healthy blood donors.

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Journal:  N Engl J Med       Date:  1988-05-26       Impact factor: 91.245

4.  Construction of the physical map for three loci in chromosome band 13q14: comparison to the genetic map.

Authors:  M J Higgins; C Turmel; J Noolandi; P E Neumann; M Lalande
Journal:  Proc Natl Acad Sci U S A       Date:  1990-05       Impact factor: 11.205

5.  Linkage disequilibria between pairs of loci within a highly polymorphic region of chromosome 2Q.

Authors:  M Litt; L B Jorde
Journal:  Am J Hum Genet       Date:  1986-08       Impact factor: 11.025

6.  HLA typing in 67 Italian patients with idiopathic hemochromatosis and their relatives.

Authors:  N Panajotopoulos; A Piperno; D Conte; C Mandelli; M Cesana; F Mercuriali; G Fiorelli; P A Bianchi; S Fargion
Journal:  Tissue Antigens       Date:  1989-04

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Authors:  L W Powell; M L Bassett; E Axelsen; J Ferluga; J W Halliday
Journal:  Ann N Y Acad Sci       Date:  1988       Impact factor: 5.691

Review 8.  The genetics of haemochromatosis.

Authors:  M Simon; P Brissot
Journal:  J Hepatol       Date:  1988-02       Impact factor: 25.083

9.  HLA class I and H ferritin gene polymorphisms in normal subjects and patients with haemochromatosis.

Authors:  S J Cragg; C Darke; M Worwood
Journal:  Hum Genet       Date:  1988-09       Impact factor: 4.132

10.  HLA class I gene polymorphism in genetic hemochromatosis.

Authors:  A M Jouanolle; J Yaouanq; M Blayau; M Périchon; R Fauchet; M P Font; J Y Le Gall; V David
Journal:  Hum Genet       Date:  1990-08       Impact factor: 4.132
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  7 in total

1.  Allelic association under map error and recombinational heterogeneity: a tale of two sites.

Authors:  C Lonjou; A Collins; R S Ajioka; L B Jorde; J P Kushner; N E Morton
Journal:  Proc Natl Acad Sci U S A       Date:  1998-09-15       Impact factor: 11.205

2.  Linkage disequilibrium and extended haplotypes in the HLA-A to D6S105 region: implications for mapping the hemochromatosis gene (HFE).

Authors:  G Gandon; A M Jouanolle; B Chauvel; V Mauvieux; A le Treut; J Feingold; J Y Le Gall; V David; J Yaouanq
Journal:  Hum Genet       Date:  1996-01       Impact factor: 4.132

3.  Physical map of the HLA-A/HLA-F subregion and identification of two new coding sequences.

Authors:  L Pichon; T Giffon; B Chauvel; G Carn; P Bouric; A El Kahloun; J Y Legall; V David
Journal:  Immunogenetics       Date:  1996       Impact factor: 2.846

4.  Anonymous marker loci within 400 kb of HLA-A generate haplotypes in linkage disequilibrium with the hemochromatosis gene (HFE)

Authors:  J Yaouanq; M Perichon; M Chorney; P Pontarotti; A Le Treut; A el Kahloun; V Mauvieux; M Blayau; A M Jouanolle; B Chauvel
Journal:  Am J Hum Genet       Date:  1994-02       Impact factor: 11.025

5.  Allelic associations and homozygosity at loci from HLA-B to D6S299 in genetic haemochromatosis.

Authors:  R Raha-Chowdhury; D J Bowen; A K Burnett; M Worwood
Journal:  J Med Genet       Date:  1995-06       Impact factor: 6.318

6.  Associations between diet quality and DSM-IV mood disorders during young- to mid-adulthood among an Australian cohort.

Authors:  Johanna E Wilson; Leigh Blizzard; Seana L Gall; Costan G Magnussen; Wendy H Oddy; Terence Dwyer; Alison J Venn; Kylie J Smith
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2021-05-07       Impact factor: 4.328

7.  New polymorphisms and markers in the HLA class I region: relevance to hereditary hemochromatosis (HFE).

Authors:  A Totaro; A Grifa; A Roetto; C Lunardi; L D'Agruma; L Sbaiz; L Zelante; G De Sandre; C Camaschella; P Gasparini
Journal:  Hum Genet       Date:  1995-04       Impact factor: 4.132
  7 in total

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