Literature DB >> 1336194

In situ demonstration of Epstein-Barr virus in intravenous drug abusers with generalized lymphadenopathy.

F Mampaso1, C Bellas, A Molina, C Quereda, T Bricio, L Buzon.   

Abstract

We have studied by the in situ hybridization method the presence of Epstein-Barr virus (EBV) DNA genome in lymph node tissues from 11 patients with persistent generalized lymphadenopathy. Using a biotinylated EBV DNA probe, we demonstrated EBV nucleic acid in scattered germinal centre cells in eight of the 11 cases. Our results suggest that EBV is not a determinant factor in the pathogenesis of this lymphadenopathy, but support its possible implication in B cell malignant transformation in cases of AIDS-associated lymphoma.

Entities:  

Mesh：

Substances：

Year:  1992        PMID： 1336194      PMCID： PMC2399456          DOI： 10.1136/pgmj.68.803.739

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN： 0032-5473            Impact factor:   2.401


  8 in total

1.  Expression of HIV in lymph node cells of LAS patients. Immunohistology, in situ hybridization, and identification of target cells.

Authors:  C D Baroni; F Pezzella; M Pezzella; B Macchi; D Vitolo; S Uccini; L P Ruco
Journal:  Am J Pathol       Date:  1988-12       Impact factor: 4.307

2.  Frequent c-myc oncogene activation and infrequent presence of Epstein-Barr virus genome in AIDS-associated lymphoma.

Authors:  M Subar; A Neri; G Inghirami; D M Knowles; R Dalla-Favera
Journal:  Blood       Date:  1988-08       Impact factor: 22.113

3.  Human immunodeficiency virus (HIV) and Epstein-Barr virus (EBV) antigens and genome in lymph nodes of HIV-positive patients affected by persistent generalized lymphadenopathy (PGL).

Authors:  S Uccini; F Monardo; D Vitolo; A Faggioni; A Gradilone; A M Aglianó; V Manzari; L P Ruco; C D Baroni
Journal:  Am J Clin Pathol       Date:  1989-12       Impact factor: 2.493

4.  Lymphadenopathies in homosexual men. Relationships with the acquired immune deficiency syndrome.

Authors:  H L Ioachim; C W Lerner; M L Tapper
Journal:  JAMA       Date:  1983-09-09       Impact factor: 56.272

5.  Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells.

Authors:  R Dalla-Favera; M Bregni; J Erikson; D Patterson; R C Gallo; C M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  1982-12       Impact factor: 11.205

6.  Detection of viral genomes in cultured cells and paraffin-embedded tissue sections using biotin-labeled hybridization probes.

Authors:  D J Brigati; D Myerson; J J Leary; B Spalholz; S Z Travis; C K Fong; G D Hsiung; D C Ward
Journal:  Virology       Date:  1983-04-15       Impact factor: 3.616

7.  A distinctive follicular hyperplasia in the acquired immune deficiency syndrome (AIDS) and the AIDS related complex. A pre-lymphomatous state for B cell lymphomas?

Authors:  P R Meyer; E T Yanagihara; J W Parker; R J Lukes
Journal:  Hematol Oncol       Date:  1984 Oct-Dec       Impact factor: 5.271

8.  Multiple monoclonal B cell expansions and c-myc oncogene rearrangements in acquired immune deficiency syndrome-related lymphoproliferative disorders. Implications for lymphomagenesis.

Authors:  P G Pelicci; D M Knowles; Z A Arlin; R Wieczorek; P Luciw; D Dina; C Basilico; R Dalla-Favera
Journal:  J Exp Med       Date:  1986-12-01       Impact factor: 14.307
  8 in total
  2 in total

1.  Antineutrophil Cytoplasmic Autoantibody Associated Systemic Vasculitis Is Associated with Epstein - Barr virus in the Setting of HIV Infection.

Authors:  Mehdi Mirsaeidi; Fatima Syed; Elaine S Jaffe
Journal:  Infect Dis Clin Pract (Baltim Md)       Date:  2013-01

2.  Detection of Epstein-Barr genome in the lymph nodes of Hodgkin's disease.

Authors:  C Bellas; F Mampaso; G Fraile; A Molina; T Bricio; C Cuesta
Journal:  Postgrad Med J       Date:  1993-12       Impact factor: 2.401
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.