Literature DB >> 13263485

Amino acid composition and electrophoretic properties of hypertensin I.

L T SKEGGS, W H MARSH, J R KAHN, N P SHUMWAY.   

Abstract

A preparation of hypertensin I was purified by countercurrent distribution and was shown to migrate as a single component in starch blocks at pH 9.3 and 4.2. It had an isoelectric point of 7.7. Quantitative analysis by ion exchange column chromatography showed eight amino acids in approximately unimolar proportion: aspartic, proline, valine, isoleucine, leucine, tyrosine, phenylalanine, and arginine. There were in addition two moles of histidine.

Entities:  

Keywords:  AMINO ACIDS/determination; ANGIOTONIN

Mesh：

Substances：

Year:  1955        PMID： 13263485      PMCID： PMC2136516          DOI： 10.1084/jem.102.4.435

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  7 in total

1.  Electrophoretic properties of oxytocin.

Authors:  Henry G Kunkel; Sterling P Taylor; Vincent Du Vigneaud
Journal:  J Biol Chem       Date:  1953-02       Impact factor: 5.157

2.  A method of assaying small amounts of hypertensin.

Authors:  L T SKEGGS; J R KAHN; W H MARSH
Journal:  Lab Invest       Date:  1953 Mar-Apr       Impact factor: 5.662

3.  Chromatography of amino acids on sulfonated polystyrene resins.

Authors:  S MOORE; W H STEIN
Journal:  J Biol Chem       Date:  1951-10       Impact factor: 5.157

4.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

5.  The purification of hypertensin I.

Authors:  L T SKEGGS; W H MARSH; J R KAHN; N P SHUMWAY
Journal:  J Exp Med       Date:  1954-10-01       Impact factor: 14.307

6.  The existence of two forms of hypertensin.

Authors:  L T SKEGGS; W H MARSH; J R KAHN; N P SHUMWAY
Journal:  J Exp Med       Date:  1954-03       Impact factor: 14.307

7.  The assay of hypertensin from the arterial blood of normotensive and hypertensive human beings.

Authors:  J R KAHN; L T SKEGGS; N P SHUMWAY; P E WISENBAUGH
Journal:  J Exp Med       Date:  1952-06       Impact factor: 14.307
  7 in total
  14 in total

1.  Angiotensin-a new pressor agent.

Authors:  J R DERRICK; B ROLAND; J ANDERSON
Journal:  Ann Surg       Date:  1962-08       Impact factor: 12.969

2.  The location of renin in the rabbit kidney.

Authors:  W F COOK; G W PICKERING
Journal:  J Physiol       Date:  1959-12       Impact factor: 5.182

3.  Hypertension and the kidney. II. Experimental basis of renal hypertension.

Authors:  W S PEART
Journal:  Br Med J       Date:  1959-12-26

4.  Isolation and identification of a pepsitensin.

Authors:  M T De Fernández; A C Paladini; A E Delius
Journal:  Biochem J       Date:  1965-11       Impact factor: 3.857

Review 5.  Drug discovery in renin-angiotensin system intervention: past and future.

Authors:  Bryan Williams
Journal:  Ther Adv Cardiovasc Dis       Date:  2016-04-27

6.  Isolation and amino acid composition of human angiotensin I.

Authors:  K Arakawa; M Nakatani; A Minohara; M Nakamura
Journal:  Biochem J       Date:  1967-09       Impact factor: 3.857

Review 7.  Renin and angiotensin. A survey of some aspects.

Authors:  J J Brown; A F Lever; D L Davies; J I Robertson
Journal:  Postgrad Med J       Date:  1966-03       Impact factor: 2.401

8.  The estimation of renin in human plasma.

Authors:  J J Brown; D L Davies; A F Lever; J I Robertson; M Tree
Journal:  Biochem J       Date:  1964-12       Impact factor: 3.857

9.  The preparation and function of the hypertensin-converting enzyme.

Authors:  L T SKEGGS; J R KAHN; N P SHUMWAY
Journal:  J Exp Med       Date:  1956-03-01       Impact factor: 14.307

10.  The purification of hypertensin II.

Authors:  L T SKEGGS; J R KAHN; N P SHUMWAY
Journal:  J Exp Med       Date:  1956-03-01       Impact factor: 14.307
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