| Literature DB >> 1313930 |
T C McGuire1, D P Knowles, W C Davis, A L Brassfield, T A Stem, W P Cheevers.
Abstract
To dissect mechanisms of caprine arthritis-encephalitis lentivirus-induced arthritis, an undefined immunodominant viral glycoprotein, gp90 (G. C. Johnson, A. F. Barbet, P. Klevjer-Anderson, and T. C. McGuire, Infect. Immun. 41:657-665, 1983), was characterized. Monoclonal antibody to gp90 and specific antiserum to env gene products demonstrated that gp90 was a transmembrane protein (TM) dimer. Goats with progressive arthritis had high antibody titers to oligomeric and monomeric (38-kDa) TM.Entities:
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Year: 1992 PMID: 1313930 PMCID: PMC241096
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103