Literature DB >> 131313

Hypertrophy and hyperplasia of somatostatin-containing D-cells in diabetes.

L Orci, D Baetens, C Rufener, M Amherdt, M Ravazzola, P Studer, F Malaisse-Lagae, R H Unger.   

Abstract

Insulin-, glucagon-, and somatostatin-contianing cells, identified by immunofluorescent staining, were quantitated morphometrically in sections of pancreas obtained from diabetic and nondiabetic humans and rats. Both the volume density and number of somatostatin- and glucagon-containing cells were significantly increased in the islets of juvenile-type human diabetics and of streptozotocin diabetic rats.

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Year:  1976        PMID： 131313      PMCID： PMC430269          DOI： 10.1073/pnas.73.4.1338

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  27 in total

1.  Letter: Immunohistochemical localization of somatostatin in the rat pancreas.

Authors:  G Pelletier; R Leclerc; A Arimura; A V Schally
Journal:  J Histochem Cytochem       Date:  1975-09       Impact factor: 2.479

2.  Evidence for the D-cell of the pancreas secreting somatostatin.

Authors:  L Orci; D Baetens; M P Dubois; C Rufener
Journal:  Horm Metab Res       Date:  1975-09       Impact factor: 2.936

3.  Immunoreactive somatostatin is present in discrete cells of the endocrine pancreas.

Authors:  M P Dubois
Journal:  Proc Natl Acad Sci U S A       Date:  1975-04       Impact factor: 11.205

4.  CRITICAL STAINING OF PANCREATIC ALPHA GRANULES WITH PHOSPHOTUNGSTIC ACID HEMATOXYLIN.

Authors:  C LEVENE; P FENG
Journal:  Stain Technol       Date:  1964-01

5.  Long-term changes of the alpha1 and alpha2 cells in the islets of Langerhans of rats with alloxan diabetes.

Authors:  B HELLMAN; B PETERSSON
Journal:  Endocrinology       Date:  1963-02       Impact factor: 4.736

6.  Quantitative estimation of the pancreatic islet tissue in diabetic subjects.

Authors:  N MACLEAN; R F OGILVIE
Journal:  Diabetes       Date:  1955 Sep-Oct       Impact factor: 9.461

7.  Growth-hormone release-inhibiting hormone in gastrointestinal and pancreatic D cells.

Authors:  J M Polak; A G Pearse; L Grimelius; S R Bloom
Journal:  Lancet       Date:  1975-05-31       Impact factor: 79.321

8.  Somatostatin: abundance of immunoreactive hormone in rat stomach and pancreas.

Authors:  A Arimura; H Sato; A Dupont; N Nishi; A V Schally
Journal:  Science       Date:  1975-09-19       Impact factor: 47.728

9.  Increased somatostatin content of islets from streptozotocin-diabetic rats.

Authors:  Y C Patel; G C Weir
Journal:  Clin Endocrinol (Oxf)       Date:  1976-03       Impact factor: 3.478

10.  Studies on antibody production. I. A method for the histochemical demonstration of specific antibody and its application to a study of the hyperimmune rabbit.

Authors:  A H COONS; E H LEDUC; J M CONNOLLY
Journal:  J Exp Med       Date:  1955-07-01       Impact factor: 14.307
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  69 in total

1.  Virus-induced diabetes in mice: a quantitative evaluation of islet cell population by immunofluorescence technique.

Authors:  Y Stefan; F Malaisse-Lagae; J W Yoon; A L Notkins; L Orci
Journal:  Diabetologia       Date:  1978-11       Impact factor: 10.122

2.  Determination of Optimal Sample Size for Quantification of β-Cell Area, Amyloid Area and β-Cell Apoptosis in Isolated Islets.

Authors:  Daniel T Meier; Leon Entrup; Andrew T Templin; Meghan F Hogan; Thanya Samarasekera; Sakeneh Zraika; Edward J Boyko; Steven E Kahn
Journal:  J Histochem Cytochem       Date:  2015-08       Impact factor: 2.479

3.  Delta cell death in the islet of Langerhans and the progression from normal glucose tolerance to type 2 diabetes in non-human primates (baboon, Papio hamadryas).

Authors:  Rodolfo Guardado Mendoza; Carla Perego; Giovanna Finzi; Stefano La Rosa; Carlo Capella; Lilia M Jimenez-Ceja; Licio A Velloso; Mario J A Saad; Fausto Sessa; Federico Bertuzzi; Stefania Moretti; Edward J Dick; Alberto M Davalli; Franco Folli
Journal:  Diabetologia       Date:  2015-06-07       Impact factor: 10.122

4.  Regulation of pancreatic PC1 and PC2 associated with increased glucagon-like peptide 1 in diabetic rats.

Authors:  Y Nie; M Nakashima; P L Brubaker; Q L Li; R Perfetti; E Jansen; Y Zambre; D Pipeleers; T C Friedman
Journal:  J Clin Invest       Date:  2000-04       Impact factor: 14.808

5.  Pancreatic immunoreactive somatostatin release.

Authors:  G S Patton; E Ipp; R E Dobbs; L Orci; W Vale; R H Unger
Journal:  Proc Natl Acad Sci U S A       Date:  1977-05       Impact factor: 11.205

6.  Hyperplasia of "pancreatic polypeptide"-cells in the pancreas of juvenile diabetics.

Authors:  W Gepts; J De Mey; M Marichal-Pipeleers
Journal:  Diabetologia       Date:  1977-01       Impact factor: 10.122

7.  Islet cell surface and lymphocyte antibodies often precede the spontaneous diabetes in the BB rat.

Authors:  T Dyrberg; P Poussier; F Nakhooda; E B Marliss; A Lernmark
Journal:  Diabetologia       Date:  1984-02       Impact factor: 10.122

8.  Acute effects of alloxan- and streptozotocin-induced insulin deficiency on somatostatin and glucagon secretion by the perfused isolated rat pancreatico-duodenal preparation.

Authors:  Y Goto; M Berelowitz; L A Frohman
Journal:  Diabetologia       Date:  1981       Impact factor: 10.122

9.  Insulin signaling in alpha cells modulates glucagon secretion in vivo.

Authors:  Dan Kawamori; Amarnath J Kurpad; Jiang Hu; Chong Wee Liew; Judy L Shih; Eric L Ford; Pedro L Herrera; Kenneth S Polonsky; Owen P McGuinness; Rohit N Kulkarni
Journal:  Cell Metab       Date:  2009-04       Impact factor: 27.287

10.  Functional and morphological differentiation of fetal porcine islet-like cell clusters after transplantation into nude mice.

Authors:  O Korsgren; L Jansson; D Eizirik; A Andersson
Journal:  Diabetologia       Date:  1991-06       Impact factor: 10.122
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