Literature DB >> 131661

Increased somatostatin content of islets from streptozotocin-diabetic rats.

Y C Patel, G C Weir.   

Abstract

Pancreatic islets were isolated from control and streptozotocin-diabetic rats. Somatostatin content as determined by radioimmunoassay was strikingly increased in the diabetic group. Immunoreactive insulin content was markedly reduced and glucagon was moderately increased. The mechanisms responsible for the somatostatin changes are unknown.

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Year:  1976        PMID： 131661     DOI： 10.1111/j.1365-2265.1976.tb02832.x

Source DB:  PubMed          Journal:  Clin Endocrinol (Oxf)        ISSN： 0300-0664            Impact factor:   3.478


  24 in total

1.  The evaluation of serum amylase in the patients of type 2 diabetes mellitus, with a possible correlation with the pancreatic functions.

Authors:  Rakhee Yadav; Jai Prakash Bhartiya; Sunil Kumar Verma; Manoj Kumar Nandkeoliar
Journal:  J Clin Diagn Res       Date:  2013-07-01

2.  Malic enzyme is present in mouse islets and modulates insulin secretion.

Authors:  J Xu; J Han; Y S Long; J Lock; G C Weir; P N Epstein; Y Q Liu
Journal:  Diabetologia       Date:  2008-09-19       Impact factor: 10.122

3.  Somatostatin in the pancreas, stomach and hypothalamus of the diabetic Chinese hamster.

Authors:  B Petersson; R Elde; S Efendić; T Hökfelt; O Johansson; R Luft; E Cerasi; C Hellerström
Journal:  Diabetologia       Date:  1977-09       Impact factor: 10.122

4.  Abundance of somatostatin cells in the human neonatal pancreas.

Authors:  J Rahier; J Wallon; J C Henquin
Journal:  Diabetologia       Date:  1980-03       Impact factor: 10.122

Review 5.  Secretion of somatostatin from the normal and diabetic pancreas. Studies in vitro.

Authors:  K Hermansen
Journal:  Diabetologia       Date:  1980       Impact factor: 10.122

6.  Pancreatic immunoreactive somatostatin release.

Authors:  G S Patton; E Ipp; R E Dobbs; L Orci; W Vale; R H Unger
Journal:  Proc Natl Acad Sci U S A       Date:  1977-05       Impact factor: 11.205

7.  The role of rosiglitazone treatment in the modulation of islet hormones and hormone-like peptides: a combined in situ hybridization and immunohistochemical study.

Authors:  Sukriye Yildirim; Sema Bolkent; Frank Sundler
Journal:  J Mol Histol       Date:  2008-11-08       Impact factor: 2.611

8.  Acute effects of alloxan- and streptozotocin-induced insulin deficiency on somatostatin and glucagon secretion by the perfused isolated rat pancreatico-duodenal preparation.

Authors:  Y Goto; M Berelowitz; L A Frohman
Journal:  Diabetologia       Date:  1981       Impact factor: 10.122

9.  Somatostatin-like immunoreactivity in rat blood. Characterization, regional differences, and responses to oral and intravenous glucose.

Authors:  M Berelowitz; S Kronheim; B Pimstone; B Shapiro
Journal:  J Clin Invest       Date:  1978-05       Impact factor: 14.808

10.  Comparison of somatostatin distribution in pancreatic duct ligated rats and streptozotocin diabetic rats.

Authors:  W Lee; H Wakasugi; H Ibayashi
Journal:  Gastroenterol Jpn       Date:  1983-10
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