Literature DB >> 129970

[On the carcinogenic action of N-nitroso-compounds. 5th Communication: acetoxymethyl-methyl-nitrosamine (author's transl)].

M Wiessler, D Schmähl.   

Abstract

After oral application of 3.5 and 1.75 mg/kg Acetoxymethyl-Methyl-nitrosamine to Sprague-Dawley rats twice weekly, more than 80% of the animals developed squamous cell carcinomas of the forestomach after 6 months.

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Year:  1976        PMID： 129970     DOI： 10.1007/bf00308128

Source DB:  PubMed          Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol        ISSN： 0084-5353


  1 in total

1.  [Organotropic carcinogenic effects of 65 various N-nitroso- compounds on BD rats].

Authors:  H Druckrey; R Preussmann; S Ivankovic; D Schmähl
Journal:  Z Krebsforsch       Date:  1967
  1 in total
  17 in total

1.  Carcinogenicity of small doses of inhaled N-nitrosoacetoxymethyl-N-methylamine in Syrian golden hamsters.

Authors:  R G Klein; P Schmezer; D Komitowski
Journal:  J Cancer Res Clin Oncol       Date:  1986       Impact factor: 4.553

2.  Some aspects of metabolic activation of chemical carcinogens in relation to their organ specificity.

Authors:  H Bartsch; G P Margison; C Malaveille; A M Camus; G Brun; J M Margison; G F Kolar; M Wiessler
Journal:  Arch Toxicol       Date:  1977-12-30       Impact factor: 5.153

3.  [Selective induction of tumors in Wistar rats with loop colostomy after administration of methyl-(acetoxymethyl)-nitrosamine (MAOMN) (author's transl)].

Authors:  J Doertenbach; S Ivankovic; K Junghanns; A Siebert; J Hettler; M Wiessler; L von Gerstenbergk
Journal:  J Cancer Res Clin Oncol       Date:  1981       Impact factor: 4.553

4.  Embryotoxicity induced by alkylating agents: left-sided preponderance of paw malformations induced by acetoxymethyl-methylnitrosamine in mice.

Authors:  G Bochert; T Platzek; G Blankenburg; M Wiessler; D Neubert
Journal:  Arch Toxicol       Date:  1985-01       Impact factor: 5.153

5.  [On the carcinogenetic action of N-nitroso compounds. 7th communication: methyl-, trideuteromethyl-, ethyl-, n-propyl-, n-butyl-, acetoxymethyl-nitrosamine, and methyl-butyroxymethyl-nitrosamine (author's transl)].

Authors:  M Wiessler; M Habs; D Schmähl
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1978

6.  Chemotherapy studies in autochthonous rat tumors intestinal cancer.

Authors:  F Sych; M Habs; D Schmähl
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1978-08-24

7.  Interference of acetoxyalkyl-nitrosamines with limb bud differentiation in organ culture.

Authors:  R Stahlmann; U Bluth; M Wiessler; D Neubert
Journal:  Arch Toxicol       Date:  1983-10       Impact factor: 5.153

8.  Chemotherapeutic studies on N-nitrosoacetoxymethyl-methylamine-and 1,2-dimethylhydrazine-induced colonic tumors in rats: monotherapy with 5-fluorouracil, ftorafur, CGP 6809, and CGP 15'720A.

Authors:  I Wagner; M Habs; D Schmähl; H Amberger; U Bachmann
Journal:  J Cancer Res Clin Oncol       Date:  1982       Impact factor: 4.553

9.  Induction of gastric tumors in BD-VI rats by single application of N-methyl-N'-nitro-N-nitrosoguanidine in dimethylsulfoxide (DMSO).

Authors:  M Habs; R Deutsch-Wenzel; R Preussmann; D Schmähl
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1978-05-31

10.  Carcinogenicity of acetoxymethyl-methyl-nitrosamine after subcutaneous, intravenous and intrarectal applications in rats.

Authors:  M Habs; D Schmähl; M Wiessler
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1978-05-31
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