Literature DB >> 12960907

Prognostic factors for survival in metastatic spinal cord compression: a retrospective study in a rehabilitation setting.

Ying Guo1, Beth Young, J Lynn Palmer, Yong Mun, Eduardo Bruera.   

Abstract

OBJECTIVE: Metastatic spinal cord compression (MSCC) occurs in 5-10% of all patients with cancer, and it is associated with short survival durations. Patients with MSCC may also have functional loss and require rehabilitation before discharge from the hospital. The purposes of this retrospective study were to identify clinical and social variables that had a significant impact on survival of patients with MSCC who underwent inpatient rehabilitation.
DESIGN: A total of 60 consecutive patients with MSCC who were admitted to the inpatient rehabilitation unit at our tertiary care cancer center between 1996 and 1998 were included. Age, discharge destination, primary tumor site, metastasis, comorbidity, hemoglobin and albumin levels, treatment rendered for MSCC, opioids used, and psychological symptoms were examined as variables, and the Kaplan-Meier survival analysis was used.
RESULTS: Our study showed that most of the variables we examined had no significant influence on survival time (median, 4.1 mo), with the exception of gastrointestinal cancer; patients with gastrointestinal cancer had a poorer prognosis (median survival durations, 0.6 mo; P < 0.0001). We also found a 1-mo gap between the time of diagnosis and the time of transfer to the rehabilitation unit.
CONCLUSION: This study suggests that rehabilitation programs for patients with MSCC should be of short duration and that early referral (i.e., when the patient is diagnosed of MSCC) to the rehabilitation service should be encouraged.

Entities:  

Mesh:

Year:  2003        PMID: 12960907     DOI: 10.1097/01.PHM.0000083662.85497.1F

Source DB:  PubMed          Journal:  Am J Phys Med Rehabil        ISSN: 0894-9115            Impact factor:   2.159


  10 in total

Review 1.  Rehabilitation and treatment of spinal cord tumors.

Authors:  Vishwa S Raj; Latanya Lofton
Journal:  J Spinal Cord Med       Date:  2013-01       Impact factor: 1.985

Review 2.  Metastasis to nervous system: spinal epidural and intramedullary metastases.

Authors:  Melike Mut; David Schiff; Mark E Shaffrey
Journal:  J Neurooncol       Date:  2005-10       Impact factor: 4.130

3.  Cancer rehabilitation: a barometer for survival?

Authors:  Takako Saotome; Linda Klein; Steven Faux
Journal:  Support Care Cancer       Date:  2015-03-05       Impact factor: 3.603

4.  Advance directives and do-not-resuscitate orders in patients with cancer with metastatic spinal cord compression: advanced care planning implications.

Authors:  Ying Guo; J Lynn Palmer; Josephine Bianty; Benedict Konzen; Ki Shin; Eduardo Bruera
Journal:  J Palliat Med       Date:  2010-05       Impact factor: 2.947

5.  Survival after rehabilitation for spinal cord injury due to tumor: a 12-year retrospective study.

Authors:  Michael Tan; Peter New
Journal:  J Neurooncol       Date:  2010-11-23       Impact factor: 4.130

6.  Inpatient rehabilitation outcomes in patients with malignant spinal cord compression compared to other non-traumatic spinal cord injury: A population based study.

Authors:  Christian D Fortin; Jennifer Voth; Susan B Jaglal; B Catharine Craven
Journal:  J Spinal Cord Med       Date:  2015-01-23       Impact factor: 1.985

7.  Inpatient rehabilitation outcomes in neoplastic spinal cord compression vs. traumatic spinal cord injury.

Authors:  Sevgi Ikbali Afsar; Sacide Nur Saraçgil Cosar; Oya Umit Yemişçi; Hüma Bölük
Journal:  J Spinal Cord Med       Date:  2020-07-23       Impact factor: 1.985

8.  Malignant spinal cord compression: a retrospective audit of clinical practice at a UK regional cancer centre.

Authors:  A McLinton; C Hutchison
Journal:  Br J Cancer       Date:  2006-02-27       Impact factor: 7.640

9.  Management of Metastatic Spinal Cord Compression in Secondary Care: A Practice Reflection from Medway Maritime Hospital, Kent, UK.

Authors:  Sidrah Shah; Mikolaj Kutka; Kathryn Lees; Charlotte Abson; Maher Hadaki; Deirdre Cooke; Cherie Neill; Matin Sheriff; Afroditi Karathanasi; Stergios Boussios
Journal:  J Pers Med       Date:  2021-02-09

10.  Early rehabilitation improves neurofunctional outcome after surgery in children with spinal tumors.

Authors:  Nezire Kose; Ozge Muezzinoglu; Sevil Bilgin; Sevilay Karahan; Ilkay Isikay; Burcak Bilginer
Journal:  Neural Regen Res       Date:  2014-01-15       Impact factor: 5.135

  10 in total

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