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Literature DB >> 12952913

Hypertension: beta testing.

Abstract

A new study demonstrates that angiotensin-induced hypertension results in a marked decrease in expression of the beta subunit of the BK channel, suggesting a role for this critical subunit in the regulation of vascular tone.

Entities: Disease

Mesh：

Substances：

Year: 2003 PMID： 12952913 PMCID： PMC182214 DOI： 10.1172/JCI19580

Source DB: PubMed Journal: J Clin Invest ISSN： 0021-9738 Impact factor: 14.808

13 in total

1. Mice with disrupted BK channel beta1 subunit gene feature abnormal Ca(2+) spark/STOC coupling and elevated blood pressure.

Authors: S Plüger; J Faulhaber; M Fürstenau; M Löhn; R Waldschütz; M Gollasch; H Haller; F C Luft; H Ehmke; O Pongs
Journal: Circ Res Date: 2000-11-24 Impact factor: 17.367

Review 2. New disguises for an old channel: MaxiK channel beta-subunits.

Authors: Patricio Orio; Patricio Rojas; Gonzalo Ferreira; Ramón Latorre
Journal: News Physiol Sci Date: 2002-08

3. Smooth muscle-specific expression of the smooth muscle myosin heavy chain gene in transgenic mice requires 5'-flanking and first intronic DNA sequence.

Authors: C S Madsen; C P Regan; J E Hungerford; S L White; I Manabe; G K Owens
Journal: Circ Res Date: 1998-05-04 Impact factor: 17.367

4. Primary sequence and immunological characterization of beta-subunit of high conductance Ca(2+)-activated K+ channel from smooth muscle.

Authors: H G Knaus; K Folander; M Garcia-Calvo; M L Garcia; G J Kaczorowski; M Smith; R Swanson
Journal: J Biol Chem Date: 1994-06-24 Impact factor: 5.157

5. Vasoregulation by the beta1 subunit of the calcium-activated potassium channel.

Authors: R Brenner; G J Peréz; A D Bonev; D M Eckman; J C Kosek; S W Wiler; A J Patterson; M T Nelson; R W Aldrich
Journal: Nature Date: 2000-10-19 Impact factor: 49.962

6. Acute activation of Maxi-K channels (hSlo) by estradiol binding to the beta subunit.

Authors: M A Valverde; P Rojas; J Amigo; D Cosmelli; P Orio; M I Bahamonde; G E Mann; C Vergara; R Latorre
Journal: Science Date: 1999-09-17 Impact factor: 47.728

Review 7. Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal diseases.

Authors: S Kim; H Iwao
Journal: Pharmacol Rev Date: 2000-03 Impact factor: 25.468

8. Relaxation of arterial smooth muscle by calcium sparks.

Authors: M T Nelson; H Cheng; M Rubart; L F Santana; A D Bonev; H J Knot; W J Lederer
Journal: Science Date: 1995-10-27 Impact factor: 47.728

9. Genome-wide mapping of human loci for essential hypertension.

Authors: Mark Caulfield; Patricia Munroe; Janine Pembroke; Nilesh Samani; Anna Dominiczak; Morris Brown; Nigel Benjamin; John Webster; Peter Ratcliffe; Suzanne O'Shea; Jeanette Papp; Elizabeth Taylor; Richard Dobson; Joanne Knight; Stephen Newhouse; Joel Hooper; Wai Lee; Nick Brain; David Clayton; G Mark Lathrop; Martin Farrall; John Connell
Journal: Lancet Date: 2003-06-21 Impact factor: 79.321

10. Modulation of the molecular composition of large conductance, Ca(2+) activated K(+) channels in vascular smooth muscle during hypertension.

Authors: Gregory C Amberg; Adrian D Bonev; Charles F Rossow; Mark T Nelson; Luis F Santana
Journal: J Clin Invest Date: 2003-09 Impact factor: 14.808

4 in total