Literature DB >> 12136044

New disguises for an old channel: MaxiK channel beta-subunits.

Patricio Orio1, Patricio Rojas, Gonzalo Ferreira, Ramón Latorre.   

Abstract

Ca(2+)-activated K(+) channels of large conductance (MaxiK or BK channels) control a large variety of physiological processes, including smooth muscle tone, neurosecretion, and hearing. Despite being coded by a single gene (Slowpoke), the diversity of MaxiK channels is great. Regulatory b-subunits, splicing, and metabolic regulation create this diversity fundamental to the adequate function of many tissues.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 12136044     DOI： 10.1152/nips.01387.2002

Source DB:  PubMed          Journal:  News Physiol Sci        ISSN： 0886-1714


  160 in total

1.  An endoplasmic reticulum trafficking signal prevents surface expression of a voltage- and Ca2+-activated K+ channel splice variant.

Authors:  M M Zarei; M Eghbali; A Alioua; M Song; H-G Knaus; E Stefani; L Toro
Journal:  Proc Natl Acad Sci U S A       Date:  2004-06-28       Impact factor: 11.205

2.  Molecular mechanism of pharmacological activation of BK channels.

Authors:  Guido Gessner; Yong-Mei Cui; Yuko Otani; Tomohiko Ohwada; Malle Soom; Toshinori Hoshi; Stefan H Heinemann
Journal:  Proc Natl Acad Sci U S A       Date:  2012-02-13       Impact factor: 11.205

3.  Highly specific alternative splicing of transcripts encoding BK channels in the chicken's cochlea is a minor determinant of the tonotopic gradient.

Authors:  Soledad Miranda-Rottmann; Andrei S Kozlov; A J Hudspeth
Journal:  Mol Cell Biol       Date:  2010-05-17       Impact factor: 4.272

Review 4.  Allosteric interactions and the modular nature of the voltage- and Ca2+-activated (BK) channel.

Authors:  Ramon Latorre; Francisco J Morera; Cristian Zaelzer
Journal:  J Physiol       Date:  2010-07-05       Impact factor: 5.182

Review 5.  Ca(v)1.3 and BK channels for timing and regulating cell firing.

Authors:  David Henry Vandael; Andrea Marcantoni; Satyajit Mahapatra; Anton Caro; Peter Ruth; Annalisa Zuccotti; Marlies Knipper; Emilio Carbone
Journal:  Mol Neurobiol       Date:  2010-11-20       Impact factor: 5.590

6.  Neuronal fast activating and meningeal silent modulatory BK channel splice variants cloned from rat.

Authors:  Asser Nyander Poulsen; Inger Jansen-Olesen; Jes Olesen; Dan Arne Klaerke
Journal:  Pflugers Arch       Date:  2010-10-12       Impact factor: 3.657

7.  BK channels play a counter-adaptive role in drug tolerance and dependence.

Authors:  Alfredo Ghezzi; Jascha B Pohl; Yan Wang; Nigel S Atkinson
Journal:  Proc Natl Acad Sci U S A       Date:  2010-08-26       Impact factor: 11.205

8.  Optimization of gene delivery methods in Xenopus laevis kidney (A6) and Chinese hamster ovary (CHO) cell lines for heterologous expression of Xenopus inner ear genes.

Authors:  Daniel Ramirez-Gordillo; Casilda Trujillo-Provencio; V Bleu Knight; Elba E Serrano
Journal:  In Vitro Cell Dev Biol Anim       Date:  2011-09-30       Impact factor: 2.416

9.  Dietary cholesterol protects against alcohol-induced cerebral artery constriction.

Authors:  Anna Bukiya; Alejandro M Dopico; Charles W Leffler; Alexander Fedinec
Journal:  Alcohol Clin Exp Res       Date:  2014-03-03       Impact factor: 3.455

10.  Statin therapy exacerbates alcohol-induced constriction of cerebral arteries via modulation of ethanol-induced BK channel inhibition in vascular smooth muscle.

Authors:  Maria N Simakova; Shivantika Bisen; Alex M Dopico; Anna N Bukiya
Journal:  Biochem Pharmacol       Date:  2017-09-01       Impact factor: 5.858
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.