Literature DB >> 12939888

Distinguishing patients with chronic fatigue from those with chronic fatigue syndrome: a diagnostic study in UK primary care.

L Darbishire1, L Ridsdale, P T Seed.   

Abstract

BACKGROUND: Chronic fatigue syndrome (CFS) has been defined, but many more patients consult in primary care with chronic fatigue that does not meet the criteria for CFS. General practitioners (GPs) do not generally use the CFS diagnosis, and have some doubt about the validity of CFS as an illness. AIM: To describe the proportion of patients consulting their GP for fatigue that met the criteria for CFS, and to describe the social, psychological, and physical differences between patients with CFS and those with non-CFS chronic fatigue in primary care. DESIGN OF STUDY: Baseline data from a trial of complex interventions for fatigue in primary care.
SETTING: Twenty-two general practices located in London and the South Thames region of the United Kingdom recruited patients to the study between 1999 and 2001.
METHOD: One hundred and forty-one patients who presented to their GP with unexplained fatigue lasting six months or more as a main symptom were recruited, and the Centers for Disease Control (CDC) case definition was applied to classify CFS.
RESULTS: Approximately two-thirds (69%) of patients had chronic fatigue and not CFS. The duration of fatigue (32 months) and perceived control over fatigue were similar between groups; however, fatigue, functioning, associated symptoms, and psychological distress were more severe in the patients in the CFS group, who also consulted their GP significantly more frequently, were twice as likely to be depressed, and more than twice as likely to be unemployed. About half (CFS = 50%; chronic fatigue = 55%) in each group attributed their fatigue to mainly psychological causes.
CONCLUSIONS: In primary care, CFS is a more severe illness than chronic fatigue, but non-CFS chronic fatigue is associated with significant fatigue and is reported at least twice as often. That half of patients, irrespective of CFS status, attribute their fatigue to psychological causes, more than is observed in secondary care, indicates an openness to the psychological therapies provided in that setting. More evidence on the natural history of chronic fatigue and CFS in primary care is required, as are trials of complex interventions. The results may help determine the usefulness of differentiating between chronic fatigue and CFS.

Entities:  

Mesh:

Year:  2003        PMID: 12939888      PMCID: PMC1314617     

Source DB:  PubMed          Journal:  Br J Gen Pract        ISSN: 0960-1643            Impact factor:   5.386


  10 in total

1.  Chronic fatigue in general practice: is counselling as good as cognitive behaviour therapy? A UK randomised trial.

Authors:  L Ridsdale; E Godfrey; T Chalder; P Seed; M King; P Wallace; S Wessely
Journal:  Br J Gen Pract       Date:  2001-01       Impact factor: 5.386

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3.  The economic cost of chronic fatigue and chronic fatigue syndrome in UK primary care.

Authors:  P McCrone; L Darbishire; L Ridsdale; P Seed
Journal:  Psychol Med       Date:  2003-02       Impact factor: 7.723

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5.  The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group.

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Journal:  Ann Intern Med       Date:  1994-12-15       Impact factor: 25.391

6.  Cognitive behavior therapy for chronic fatigue syndrome: a randomized controlled trial.

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7.  Chronic debilitating fatigue in Irish general practice: a survey of general practitioners' experience.

Authors:  E J Fitzgibbon; D Murphy; K O'Shea; C Kelleher
Journal:  Br J Gen Pract       Date:  1997-10       Impact factor: 5.386

8.  Clarifying the relationship between unexplained chronic fatigue and psychiatric morbidity: results from a community survey in Great Britain.

Authors:  P Skapinakis; G Lewis; H Meltzer
Journal:  Am J Psychiatry       Date:  2000-09       Impact factor: 18.112

9.  The hospital anxiety and depression scale.

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Journal:  Acta Psychiatr Scand       Date:  1983-06       Impact factor: 6.392

10.  Chronic fatigue: risk factors for symptom persistence in a 2 1/2-year follow-up study.

Authors:  M R Clark; W Katon; J Russo; P Kith; M Sintay; D Buchwald
Journal:  Am J Med       Date:  1995-02       Impact factor: 4.965

  10 in total
  15 in total

Review 1.  Physical activity and feelings of energy and fatigue: epidemiological evidence.

Authors:  Timothy W Puetz
Journal:  Sports Med       Date:  2006       Impact factor: 11.136

Review 2.  The Invisible Burden of Chronic Fatigue in the Community: a Narrative Review.

Authors:  Scott J Fatt; Erin Cvejic; Andrew R Lloyd; Ute Vollmer-Conna; Jessica Elise Beilharz
Journal:  Curr Rheumatol Rep       Date:  2019-02-11       Impact factor: 4.592

3.  Same, Same But Different? Cognitive Behavioural Treatment Approaches for Paediatric CFS/ME and Depression.

Authors:  M E Loades; T Chalder
Journal:  Behav Cogn Psychother       Date:  2017-03-09

4.  Nurse led, home based self help treatment for patients in primary care with chronic fatigue syndrome: randomised controlled trial.

Authors:  Alison J Wearden; Christopher Dowrick; Carolyn Chew-Graham; Richard P Bentall; Richard K Morriss; Sarah Peters; Lisa Riste; Gerry Richardson; Karina Lovell; Graham Dunn
Journal:  BMJ       Date:  2010-04-23

5.  A Chronic Fatigue Syndrome (CFS) severity score based on case designation criteria.

Authors:  James N Baraniuk; Oluwatoyin Adewuyi; Samantha Jean Merck; Mushtaq Ali; Murugan K Ravindran; Christian R Timbol; Rakib Rayhan; Yin Zheng; Uyenphuong Le; Rania Esteitie; Kristina N Petrie
Journal:  Am J Transl Res       Date:  2013-01-21       Impact factor: 4.060

6.  The effect of counselling, graded exercise and usual care for people with chronic fatigue in primary care: a randomized trial.

Authors:  L Ridsdale; M Hurley; M King; P McCrone; N Donaldson
Journal:  Psychol Med       Date:  2012-02-28       Impact factor: 7.723

7.  Social support needs for equity in health and social care: a thematic analysis of experiences of people with chronic fatigue syndrome/myalgic encephalomyelitis.

Authors:  Jose C de Carvalho Leite; Maria de L Drachler; Anne Killett; Swati Kale; Luis Nacul; Maggie McArthur; Chia Swee Hong; Lucy O'Driscoll; Derek Pheby; Peter Campion; Eliana Lacerda; Fiona Poland
Journal:  Int J Equity Health       Date:  2011-11-02

8.  The definition of disabling fatigue in children and adolescents.

Authors:  Tom Fowler; Pamela Duthie; Anita Thapar; Anne Farmer
Journal:  BMC Fam Pract       Date:  2005-08-09       Impact factor: 2.497

9.  Common and unique associated factors for medically unexplained chronic widespread pain and chronic fatigue.

Authors:  J McBeth; B Tomenson; C A Chew-Graham; G J Macfarlane; J Jackson; A Littlewood; F H Creed
Journal:  J Psychosom Res       Date:  2015-10-19       Impact factor: 3.006

10.  Protocol for the PACE trial: a randomised controlled trial of adaptive pacing, cognitive behaviour therapy, and graded exercise, as supplements to standardised specialist medical care versus standardised specialist medical care alone for patients with the chronic fatigue syndrome/myalgic encephalomyelitis or encephalopathy.

Authors:  Peter D White; Michael C Sharpe; Trudie Chalder; Julia C DeCesare; Rebecca Walwyn
Journal:  BMC Neurol       Date:  2007-03-08       Impact factor: 2.474

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