Literature DB >> 1292573

Treatment of hypertension in the elderly--the end of the story?

L H Opie.   

Abstract

The elderly constitute a high-risk group in which the benefit of treatment of hypertension is now obvious. The initial drug should be a low-dose diuretic, followed by a beta-blocker. At present there are no data favoring the use of an ultra low-dose diuretic, such as 12.5 mg hydrochlorothiazide, unless there is coexisting prediabetes or gout.

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Year:  1992        PMID： 1292573     DOI： 10.1007/bf00052553

Source DB:  PubMed          Journal:  Cardiovasc Drugs Ther        ISSN： 0920-3206            Impact factor:   3.727


  19 in total

1.  Management of elderly patients with sustained hypertension.

Authors:  K Beard; C Bulpitt; H Mascie-Taylor; K O'Malley; P Sever; S Webb
Journal:  BMJ       Date:  1992-02-15

2.  Low serum cholesterol and suicide.

Authors:  H Engelberg
Journal:  Lancet       Date:  1992-03-21       Impact factor: 79.321

3.  Randomised trial of treatment of hypertension in elderly patients in primary care.

Authors:  J Coope; T S Warrender
Journal:  Br Med J (Clin Res Ed)       Date:  1986-11-01

4.  The recent trials for aspirin in the prevention of cardiovascular mortality.

Authors:  J H Chesebro; L H Opie; V Fuster
Journal:  Cardiovasc Drugs Ther       Date:  1989-06       Impact factor: 3.727

Review 5.  Further learnings from the European Working Party on High Blood Pressure in the Elderly (EWPHE) study: focus on systolic hypertension.

Authors:  K O'Malley; J P Cox; E O'Brien
Journal:  Cardiovasc Drugs Ther       Date:  1991-01       Impact factor: 3.727

6.  Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). SHEP Cooperative Research Group.

Authors: 
Journal:  JAMA       Date:  1991-06-26       Impact factor: 56.272

7.  MRC trial of treatment of mild hypertension: principal results. Medical Research Council Working Party.

Authors: 
Journal:  Br Med J (Clin Res Ed)       Date:  1985-07-13

8.  Insulin resistance, glucose intolerance and hyperinsulinemia in patients with hypertension.

Authors:  A L Swislocki; B B Hoffman; G M Reaven
Journal:  Am J Hypertens       Date:  1989-06       Impact factor: 2.689

9.  Osler's maneuver and pseudohypertension.

Authors:  F H Messerli; H O Ventura; C Amodeo
Journal:  N Engl J Med       Date:  1985-06-13       Impact factor: 91.245

10.  Medical Research Council trial of treatment of hypertension in older adults: principal results. MRC Working Party.

Authors: 
Journal:  BMJ       Date:  1992-02-15
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  4 in total

Review 1.  Treatment of hypertension in the elderly--what have we learned from the recent trials?

Authors:  P Lund-Johansen
Journal:  Cardiovasc Drugs Ther       Date:  1992-12       Impact factor: 3.727

Review 2.  Treatment of the older hypertensive: paradigms, practices, and proofs.

Authors:  A Amery; W H Birkenhäger; R Fagard; J Staessen; L Thijs; P W de Leeuw
Journal:  Cardiovasc Drugs Ther       Date:  1992-12       Impact factor: 3.727

Review 3.  Treatment of hypertension in the elderly.

Authors:  M Moser
Journal:  Cardiovasc Drugs Ther       Date:  1992-12       Impact factor: 3.727

Review 4.  Individualised selection of antihypertensive therapy.

Authors:  L H Opie
Journal:  Drugs       Date:  1993       Impact factor: 9.546
  4 in total

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