Literature DB >> 1292574

Treatment of the older hypertensive: paradigms, practices, and proofs.

A Amery, W H Birkenhäger, R Fagard, J Staessen, L Thijs, P W de Leeuw.   

Abstract

Recent outcome trials in patients above age 60 with systolo-diastolic hypertension are reviewed. The meta-analysis suggests that antihypertensive drug therapy can decrease cardiovascular and coronary mortality in selected patients. Based on these studies it is suggested that antihypertensive drug therapy is indicated in patients between age 60 and 75 when the diastolic pressure remains above 95 mmHg after repeated measurements. A target for systolic b.p. is not definitely established but a pressure of 150 mmHg may serve as a temporary proposal. Whether uncomplicated isolated systolic hypertension in symptomless patients should be treated is still under investigation.

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Year:  1992        PMID: 1292574     DOI: 10.1007/bf00052555

Source DB:  PubMed          Journal:  Cardiovasc Drugs Ther        ISSN: 0920-3206            Impact factor:   3.727


  17 in total

1.  A meta-analysis of outcome trials in elderly hypertensives.

Authors:  L Thijs; R Fagard; P Lijnen; J Staessen; R Van Hoof; A Amery
Journal:  J Hypertens       Date:  1992-10       Impact factor: 4.844

2.  Management of elderly patients with sustained hypertension.

Authors:  K Beard; C Bulpitt; H Mascie-Taylor; K O'Malley; P Sever; S Webb
Journal:  BMJ       Date:  1992-02-15

3.  Randomised trial of treatment of hypertension in elderly patients in primary care.

Authors:  J Coope; T S Warrender
Journal:  Br Med J (Clin Res Ed)       Date:  1986-11-01

Review 4.  Treatment of hypertension in the elderly--the end of the story?

Authors:  L H Opie
Journal:  Cardiovasc Drugs Ther       Date:  1992-12       Impact factor: 3.727

Review 5.  The uses of epidemiology in the study of the elderly. Report of a WHO Scientific Group on the Epidemiology of Aging.

Authors: 
Journal:  World Health Organ Tech Rep Ser       Date:  1984

6.  Relation between mortality and treated blood pressure in elderly patients with hypertension: report of the European Working Party on High Blood Pressure in the Elderly.

Authors:  J Staessen; C Bulpitt; D Clement; P De Leeuw; R Fagard; A Fletcher; F Forette; G Leonetti; A Nissinen; K O'Malley
Journal:  BMJ       Date:  1989-06-10

7.  Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). SHEP Cooperative Research Group.

Authors: 
Journal:  JAMA       Date:  1991-06-26       Impact factor: 56.272

8.  Isolated systolic hypertension in the elderly: implications of Systolic Hypertension in the Elderly Program (SHEP) for clinical practice and for the ongoing trials.

Authors:  J Staessen; R Fagard; A Amery
Journal:  J Hum Hypertens       Date:  1991-12       Impact factor: 3.012

9.  Risks and benefits in the trial of the European Working Party on High Blood Pressure in the Elderly.

Authors:  A Fletcher; A Amery; W Birkenhäger; C Bulpitt; D Clement; P de Leeuw; M L Deruyterre; A de Schaepdryver; C Dollery; R Fagard
Journal:  J Hypertens       Date:  1991-03       Impact factor: 4.844

10.  Medical Research Council trial of treatment of hypertension in older adults: principal results. MRC Working Party.

Authors: 
Journal:  BMJ       Date:  1992-02-15
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