Literature DB >> 12916036

Total synthesis of the proposed azaspiracid-1 structure, part 1: construction of the enantiomerically pure C1-C20, C21-C27, and C28-C40 fragments.

K C Nicolaou1, Yiwei Li, Noriaki Uesaka, Theocharis V Koftis, Stepan Vyskocil, Taotao Ling, Mugesh Govindasamy, Wenyuan Qian, Federico Bernal, David Y-K Chen.   

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Year:  2003        PMID: 12916036     DOI: 10.1002/anie.200351825

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


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  14 in total

1.  Synthesis of the ABCD and ABCDE ring systems of azaspiracid-1.

Authors:  Xiao-Ti Zhou; Rich G Carter
Journal:  Chem Commun (Camb)       Date:  2004-09-20       Impact factor: 6.222

Review 2.  Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance.

Authors:  K C Nicolaou; Christopher R H Hale; Christian Nilewski; Heraklidia A Ioannidou
Journal:  Chem Soc Rev       Date:  2012-06-28       Impact factor: 54.564

3.  Synthesis of the southern FGHI ring system of azaspiracid-1 and investigation into the controlling elements of C28- and C36-ketalization.

Authors:  Xiao-Ti Zhou; Liang Lu; Daniel P Furkert; Charles E Wells; Rich G Carter
Journal:  Angew Chem Int Ed Engl       Date:  2006-11-20       Impact factor: 15.336

4.  Synthesis of the C1-C26 northern portion of azaspiracid-1: kinetic versus thermodynamic control of the formation of the bis-spiroketal.

Authors:  Xiao-Ti Zhou; Rich G Carter
Journal:  Angew Chem Int Ed Engl       Date:  2006-03-03       Impact factor: 15.336

5.  Total synthesis of atrochamins F, H, I, and J through cascade reactions.

Authors:  K C Nicolaou; Troy Lister; Ross M Denton; Christine F Gelin
Journal:  Tetrahedron       Date:  2008-05-19       Impact factor: 2.457

6.  Monoclonal antibodies with orthogonal azaspiracid epitopes.

Authors:  Michael O Frederick; Sandra De Lamo Marin; Kim D Janda; K C Nicolaou; Tobin J Dickerson
Journal:  Chembiochem       Date:  2009-07-06       Impact factor: 3.164

7.  Synthesis of (S)-FTY720 vinylphosphonate analogues and evaluation of their potential as sphingosine kinase 1 inhibitors and activators.

Authors:  Zheng Liu; Neil MacRitchie; Susan Pyne; Nigel J Pyne; Robert Bittman
Journal:  Bioorg Med Chem       Date:  2013-03-07       Impact factor: 3.641

8.  Microsphere-based immunoassay for the detection of azaspiracids.

Authors:  Laura P Rodríguez; Natalia Vilariño; M Carmen Louzao; Tobin J Dickerson; K C Nicolaou; Michael O Frederick; Luis M Botana
Journal:  Anal Biochem       Date:  2013-11-08       Impact factor: 3.365

9.  Azaspiracid substituent at C1 is relevant to in vitro toxicity.

Authors:  Natalia Vilariño; K C Nicolaou; Michael O Frederick; Eva Cagide; Carmen Alfonso; Eva Alonso; Mercedes R Vieytes; Luis M Botana
Journal:  Chem Res Toxicol       Date:  2008-08-16       Impact factor: 3.739

10.  Inspirations, discoveries, and future perspectives in total synthesis.

Authors:  K C Nicolaou
Journal:  J Org Chem       Date:  2009-02-06       Impact factor: 4.354

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