Literature DB >> 12906835

The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology.

T C Terwilliger1, M S Park, G S Waldo, J Berendzen, L-W Hung, C-Y Kim, C V Smith, J C Sacchettini, M Bellinzoni, R Bossi, E De Rossi, A Mattevi, A Milano, G Riccardi, M Rizzi, M M Roberts, A R Coker, G Fossati, P Mascagni, A R M Coates, S P Wood, C W Goulding, M I Apostol, D H Anderson, H S Gill, D S Eisenberg, B Taneja, S Mande, E Pohl, V Lamzin, P Tucker, M Wilmanns, C Colovos, W Meyer-Klaucke, A W Munro, K J McLean, K R Marshall, D Leys, J K Yang, H-J Yoon, B I Lee, M G Lee, J E Kwak, B W Han, J Y Lee, S-H Baek, S W Suh, M M Komen, V L Arcus, E N Baker, J S Lott, W Jacobs, T Alber, B Rupp.   

Abstract

The TB Structural Genomics Consortium is an organization devoted to encouraging, coordinating, and facilitating the determination and analysis of structures of proteins from Mycobacterium tuberculosis. The Consortium members hope to work together with other M. tuberculosis researchers to identify M. tuberculosis proteins for which structural information could provide important biological information, to analyze and interpret structures of M. tuberculosis proteins, and to work collaboratively to test ideas about M. tuberculosis protein function that are suggested by structure or related to structural information. This review describes the TB Structural Genomics Consortium and some of the proteins for which the Consortium is in the progress of determining three-dimensional structures.

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Year:  2003        PMID: 12906835     DOI: 10.1016/s1472-9792(03)00051-9

Source DB:  PubMed          Journal:  Tuberculosis (Edinb)        ISSN: 1472-9792            Impact factor:   3.131


  36 in total

1.  Molecular modeling studies of Fatty acyl-CoA synthetase (FadD13) from Mycobacterium tuberculosis--a potential target for the development of antitubercular drugs.

Authors:  Nidhi Jatana; Sarvesh Jangid; Garima Khare; Anil K Tyagi; Narayanan Latha
Journal:  J Mol Model       Date:  2010-05-08       Impact factor: 1.810

2.  High-throughput computational and experimental techniques in structural genomics.

Authors:  Mark R Chance; Andras Fiser; Andrej Sali; Ursula Pieper; Narayanan Eswar; Guiping Xu; J Eduardo Fajardo; Thirumuruhan Radhakannan; Nebojsa Marinkovic
Journal:  Genome Res       Date:  2004-10       Impact factor: 9.043

3.  Detecting remotely related proteins by their interactions and sequence similarity.

Authors:  Jordi Espadaler; Ramón Aragüés; Narayanan Eswar; Marc A Marti-Renom; Enrique Querol; Francesc X Avilés; Andrej Sali; Baldomero Oliva
Journal:  Proc Natl Acad Sci U S A       Date:  2005-05-09       Impact factor: 11.205

4.  Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of Rv2827c from Mycobacterium tuberculosis.

Authors:  Robert Janowski; Ali Nasser Eddine; Stefan H E Kaufmann; Manfred S Weiss
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2006-07-24

5.  Solution structure of the conserved hypothetical protein Rv2302 from Mycobacterium tuberculosis.

Authors:  Garry W Buchko; Chang-Yub Kim; Thomas C Terwilliger; Michael A Kennedy
Journal:  J Bacteriol       Date:  2006-08       Impact factor: 3.490

6.  The molecular structure of Rv1873, a conserved hypothetical protein from Mycobacterium tuberculosis, at 1.38 A resolution.

Authors:  Craig R Garen; Maia M Cherney; Ernst M Bergmann; Michael N G James
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2006-11-30

7.  Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of initiation factor 1 from Mycobacterium tuberculosis.

Authors:  Georgios N Hatzopoulos; Jochen Mueller-Dieckmann
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2007-02-10

8.  Cloning, expression, purification, crystallization and preliminary X-ray studies of epoxide hydrolases A and B from Mycobacterium tuberculosis.

Authors:  Bichitra K Biswal; Grace Garen; Maia M Cherney; Craig Garen; Michael N G James
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2006-01-27

9.  The crystal structure of Rv0793, a hypothetical monooxygenase from M. tuberculosis.

Authors:  M Joanne Lemieux; Claire Ference; Maia M Cherney; Metian Wang; Craig Garen; Michael N G James
Journal:  J Struct Funct Genomics       Date:  2006-02-22

10.  Expression, purification and preliminary X-ray analysis of the C-terminal domain of an arginine repressor protein from Mycobacterium tuberculosis.

Authors:  George J Lu; Craig R Garen; Maia M Cherney; Leonid T Cherney; Cecilia Lee; Michael N G James
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2007-10-24
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