Literature DB >> 12868754

Visible light-induced nuclease activity of a ternary mono-phenanthroline copper(II) complex containing L-methionine as a photosensitizer.

Ashis K Patra1, Shanta Dhar, Munirathinam Nethaji, Akhil R Chakravarty.   

Abstract

Ternary copper(II) complex, structurally characterized as [Cu(phen)(met)(MeOH)](ClO4) (1) by X-ray crystallography, has 1,10-phenanthroline (phen) as an intercalator/binder to supercoiled pUC19 DNA and L-methionine (met) as a photosensitizer, and the complex displays efficient photonuclease activity on irradiation with UV (312 nm) or visible (436, 532 nm) light through a mechanistic pathway involving singlet oxygen.

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Year:  2003        PMID： 12868754     DOI： 10.1039/b303442a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Nuclease activity via self-activation and anticancer activity of a mononuclear copper(II) complex: novel role of the tertiary butyl group in the ligand frame.

Authors:  Kaushik Ghosh; Pramod Kumar; Varun Mohan; Udai P Singh; Sahba Kasiri; Subhrangsu S Mandal
Journal:  Inorg Chem       Date:  2012-02-28       Impact factor: 5.165

2.  Insights into the mechanisms underlying the antiproliferative potential of a Co(II) coordination compound bearing 1,10-phenanthroline-5,6-dione: DNA and protein interaction studies.

Authors:  Daniel V Luís; Joana Silva; Ana Isabel Tomaz; Rodrigo F M de Almeida; Miguel Larguinho; Pedro V Baptista; Luísa M D R S Martins; Telma F S Silva; Pedro M Borralho; Cecília M P Rodrigues; António S Rodrigues; Armando J L Pombeiro; Alexandra R Fernandes
Journal:  J Biol Inorg Chem       Date:  2014-01-31       Impact factor: 3.358

3.  Fluorescent Imidazo[1,5-a]pyridinium Salt for a Potential Cancer Therapy Agent.

Authors:  Fumitoshi Yagishita; Jun-Ichi Tanigawa; Chiho Nii; Atsushi Tabata; Hideaki Nagamune; Hiroki Takanari; Yasushi Imada; Yasuhiko Kawamura
Journal:  ACS Med Chem Lett       Date:  2019-07-24       Impact factor: 4.345
  3 in total

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